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A history illustrating the complexity of medical decision making and risk. Still the leading cause of death worldwide, heart disease challenges researchers, clinicians, and patients alike. Each day, thousands of patients and their doctors make decisions about coronary angioplasty and bypass surgery. In Broken Hearts David S. Jones sheds light on the nature and quality of those decisions. He describes the debates over what causes heart attacks and the efforts to understand such unforeseen complications of cardiac surgery as depression, mental fog, and stroke. Why do doctors and patients overestimate the effectiveness and underestimate the dangers of medical interventions, especially when doing so may lead to the overuse of medical therapies? To answer this question, Jones explores the history of cardiology and cardiac surgery in the United States and probes the ambiguities and inconsistencies in medical decision making. Based on extensive reviews of medical literature and archives, this historical perspective on medical decision making and risk highlights personal, professional, and community outcomes.
Cardiac resynchronization therapy (CRT) is one of the most exciting new advances in the treatment of chronic severe (NYHA symptom class) heart failure associated with dyssynchronous ventricular contraction that is refractory to medical treatment. In all randomized trials CR has resulted in improved NYHA symptom class, exercise capacity and quality
Written by recognized leaders in the field, Congestive Heart Failure, Third Edition is a comprehensive, state-of-the-art reference on all basic and clinical aspects of heart failure. Coverage includes an entire section on pharmacologic therapy and a twenty-chapter section on clinical approaches to acute and chronic heart failure. This edition has new chapters on impact and treatment of comorbidities, prevention of sudden cardiac death, rationale for use of anticoagulants, ultrafiltration, use of mechanical devices, and gene and cell therapy. Readers will find up-to-date information on genetics, surgical therapies, ventricular synchronization, defibrillator therapy, mechanical approaches to atrial fibrillation, left ventricular assist devices, ventricular support and ventricular remodeling surgery, and myocardial regeneration/cell transplantation.
Although clinicians have recognized the importance of inflammatory mediators in the pathogenesis of heart disease for well over 200 years, it has taken nearly as many years for clinicians and scientists to focus on the basic biological mechanisms by which inflammatory mediators contribute to the pathogenesis of cardiac disease states. Over the past decade there has been increasing interest in the potential role that inflammatory mediators, play in a variety of cardiac disease states, including chronic heart failure. The Role of Inflammatory Mediators in the Failing Heart provides a state-of-the-art review on inflammatory mediators and the failing heart. This book will serve both as a useful introduction to the field, as well as an update for those interested in the role of inflammatory mediators and the failing heart.
Physiologic compartmentalization effectively isolates the central nervous system from the rest of the body. This isolation not only provides protection of its delicate function from aberrant peripheral influences but also impedes its diagnostic evaluation. Cerebro spinal fluid (CSF) bathes the brain and spinal cord, is in dynamic equilibrium with its extracellular fluid, and tends to reflect the state of health and activity of the central nervous system. CSF examination is the most direct and popular method of assessing the central chemical and cellular environment in the living patient or mammal. The purpose of this multidisciplined reference text is to provide the sophisticated knowledge o...
Beyond political posturing and industry quick-fixes, why is the American health care system so difficult to reform? Health care reform efforts are difficult to achieve and have been historically undermined by their narrow scope. In The Present Illness, Martin F. Shapiro, MD, PhD, MPH, weaves together history, sociology, extensive research, and his own experiences as a physician to explore the broad range of afflictions impairing US health care and explains why we won't be able to fix the system without making significant changes across society. With a sharp eye and ready humor, Shapiro dissects the ways all groups participating—clinicians and their organizations, medical schools and their ...
Catalog of Catalogs provides a comprehensive index of nearly 2,300 publications documenting the exhibition of Judaica over the past 140 years. This vast corpus of material, ranging from simple leaflets to scholarly catalogs, contains textual and visual material as yet unmined for the study of Jewish art, religion, culture and history. Through highly-detailed, fully-indexed catalog entries, William Gross, Orly Tzion and Falk Wiesemann elucidate some 2,000 subjects, geographical locations and Judaica objects (ceremonial objects, illuminated manuscripts, printed books, synagogues, cemeteries et al.) addressed in these catalogs. Descriptions of the catalog's bibliographic components, contributors, exhibition history, and contents, all accessible through the volume's five indices, render this volume an unparalleled new resource for the study of Jewish Art, culture and history.