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Annotation Although it is widely recognized that environmental factors such as smoking, diet, exercise, and socioeconomic status affect the risk of cardiovascular disease, recent work showing the effects of other environmental factors provides a more complete assessment of the situation. This view has emerged from three developments. Firstly, there has been a sudden explosion in the prevalence of diabetes and obesity which indicates a strong environmental component. Secondly, there is an accumulation of evidence suggesting that most cases of these diseases could be prevented by healthy lifestyle choices. Finally, studies have shown that exposure to environmental pollutants has a significant ...
Current evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector. Each of these steps in is now its own intense area of investigation. The need to render the heart ischemic for a brief period to invoke the preconditioning response is currently the major factor limiting clinical application of this powerful cardioprotective strategy. Recent research efforts have utilized brief exposures to pharmacological agents, in lieu of a brief preconditioning ischemia, to trigger/mimic the ischemic preconditioning-induced response. The World Heart Congress held in Winnipeg in July 2001 provided a forum for the presentation of new insights into the basic mechanisms of ischemia and reperfusion injury, as well as novel strategies to protect the heart from cell death, ventricular arrhythmias, and contractile dysfunction. Many pioneers in the fields of ischemia-reperfusion injury and preconditioning-induced protection presented there and the chapters in this book represent selected papers from these symposia.
The American Heart Association’s Scientific Sessions 2016 is bringing big science, big technology, and big networking opportunities to New Orleans, Louisiana this November. This event features five days of the best in science and cardiovascular clinical practice covering all aspects of basic, clinical, population and translational content.
The largest collection of articles on the three major gene families, this work ranges from enzymology to molecular biology to physiological implications. The three gene families are related in that the enzymes catalyse the NAD(P) dependent oxidation or reduction of carbonyl containing substrates. The substrates are important in diverse areas such as alcoholism, diabetes and cancer related problems as well as simple detoxification. The scope of the chapters, contributed by leading international scientists, is wide and covers gene regulation to enzyme mechanisms and protein structure. This is the only publication dealing in such depth with just three gene families. An important reference for researchers in toxicology and molecular biology.
The American Heart Association’s Scientific Sessions 2019 is bringing big science, big technology, and big networking opportunities to Philadelphia, Pennsylvania this November. This event features five days of the best in science and cardiovascular clinical practice covering all aspects of basic, clinical, population and translational content.
Current, comprehensive, and evidence-based Braunwald's Heart Disease remains the most trusted reference in the field and the leading source of reliable cardiology information for practitioners and trainees worldwide. The fully updated 12th Edition continues the tradition of excellence with dependable, state-of-the-art coverage of new drugs, new guidelines, more powerful imaging modalities, and recent developments in precision medicine that continue to change and advance the practice of cardiovascular medicine. Written and edited by global experts in the field, this award-winning text is an unparalleled multimedia reference for every aspect of this complex and fast-changing area. - Offers bal...
The continuation of an annual series, Enzymology and Molecular Biology of Carbonyl Metabolism is the largest collection of articles on the three major gene families. The scope of the chapters, contributed by leading international scientists, is wide and covers gene regulation to enzyme mechanisms and protein structure. This is the only publication dealing in such depth with just three gene families. It is an important reference for researchers in toxicology and molecular biology.
This volume contains up-to-date information on aldehyde dehydrogenase, alcohol dehydrogenase, short- and medium-chain dehydrogenase, and reductases. Sixty-nine contributions provide a wide variety of information on enzymology, molecular biology, and metabolic aspects of these carbonyl metabolizing oxidoreductases. Much new information is provided, including previously unreported three-dimensional structures of enzymes and new aspects of gene regulation, along with sequence alignments, metabolism and enzyme mechanisms.
The book details the solution to the complex health issues faced by human dysevolution. The solution is traced after gross explanation of evolution of human design and the reasons of disruption. Grounded in science and explained with real life case studies, the solution elucidates the catalytic role and prescription of real food, right movement and healthy lifestyle. Backed by research, the author demystifies myths and debunks the hype around modern diets to explain the value of natural wholesome real foods. Detailed content on how exercise cures diseases and prescription to improve the movement deficit lifestyle has been outlined. The book concludes with integrated health framework for society, where preventive healthcare in the true sense could help in focusing all the developmental effort. Thus the book offers a holistic, long-term approach enabling the reader to reclaim the human body in the pursuit of a healthier and happier life.