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This text traces developments in rational drug discovery and combinatorial library design with contributions from 50 leading scientists in academia and industry who offer coverage of basic principles, design strategies, methodologies, software tools and algorithms, and applications. It outlines the fundamentals of pharmacophore modelling and 3D Quantitative Structure-Activity Relationships (QSAR), classical QSAR, and target protein structure-based design methods.
Each number is the catalogue of a specific school or college of the University.
This volume constitutes the proceedings of the Third IFIP WG 8.1 Working Conference on the Practice of Enterprise Modeling, held in Delft, The Netherlands, during November 9-10, 2010. The goal of the conference is both to foster a better understanding of the practice of enterprise modeling and to improve its theoretical foundations. The 17 papers presented were carefully reviewed and selected from 44 submissions. They reflect the trend for both practitioners and academics to look into domains and conceptualizations addressing dedicated business-oriented topics like business intelligence or domain-driven process families, and thus reach beyond traditional information systems engineering.
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