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This SpringerBrief provides an update on endometriosis research -- from the underlying mechanisms, predisposing factors, role of environmental pollutants, treatment options, impact on quality of life, and biomarkers, to emerging treatment modalities in order to help clinicians to pursue a patient-centered approach in managing the disease. This book provides clinicians with a better insight into early diagnosis and management of endometriosis. It explores the possible identification of proteins in different types of endometriosis diseases and at different stages of the progression. This may aid in the discovery of potential biomarkers for non-invasive diagnosis of these diseases. The ability to identify a protein, common between women of different races, ages and in different regions of the world will hopefully contribute to improving women’s health worldwide.
This book discusses the role of oxidative stress in the reproductive system. The book reviews endogenous sources, methods of determining its levels in body fluid/tissues, the physiological roles of ROS, as well as its negative effects on the human reproductive processes. Also discussed are multiple extrinsic factors that could induce oxidative stress in the reproductive system. This volume covers various clinical pathologies related to the reproductive system that arise from or produce oxidative stress, both in the male and female. The use of antioxidants as a therapeutic measure to keep ROS levels in check are highlighted, describing the outcome of various clinical studies involving antioxidant supplementation in infertile patients. Infertility is a global disease that affects 15-25% of all couples, and oxidative stress arising from a multitude of sources has been implicated as one of the major contributing factors to the decline in human fertility. As such, this book provides an up-to-date review on the significance of ROS in human reproduction.
The development of science and technology in recent decades has enabled IVF methods to occupy a leading place in the treatment of infertility. This book introduces some modern infertility treatment methods that are part of IVF technologies, focusing on clinical practice. Topics discussed include semen analysis, ovarian stimulation, and basic methods applied in the IVF laboratory. The book also addresses diagnostics and treatment of the immunological factor of infertility as well as the relationship between infertility and reproductive age. This book will increase readers’ knowledge and understanding of the treatment of infertility using in vitro technologies.
This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including SCSA, SCD, TUNEL and Comet assays, and cytochemical tests. Biological and clinical factors in the etiology of sperm DNA damage are discussed in part III, including oxidative stress, abortive apoptosis, cancer, and environmental and lifestyle factors. Part IV presents clinical studies on the utility of sperm DNA damage tests, both with natur...
A groundbreaking contribution to the literature now in its revised and expanded second edition, this textbook offers a comprehensive review of diagnostic and treatment techniques for male infertility. This state-of-the-art, evidence-based textbook incorporates new multidisciplinary and complementary medicine approaches to create a first-of-its-kind guide to treatment strategies for male infertility and beyond. While this new edition is primarily designed as a reference for students and residents in reproductive medicine and andrology, it will be equally useful as well for professionals in urology, reproductive endocrinology, embryology, and research fields who are interested in the role that...
The phenomenon of bleeding has been shown to appear in up to 22% of all pregnancies and is associated with significant maternal and fetal morbidities, and even mortality. Although vaginal bleeding occurs mainly during the first trimester, it can appear at any stage of pregnancy and in the postpartum period. This sometimes life-threatening event requires an extensive work-up in order to recognize its cause and establish a rapid and effective therapeutic approach. This book is a comprehensive appraisal of this critical condition. It draws on evidence-based data and brings together, in a single volume, updated information on all aspects of pregnancy-related bleeding. A global group of interdisciplinary experts contributed chapters on: bleeding during early pregnancy (early pregnancy loss, ectopic pregnancy, gestational trophoblastic disease, and cancer of the reproductive tract during pregnancy); bleeding in late pregnancy (preterm delivery, placental abruption, placenta previa, vasa previa and uterine rupture); and postpartum hemorrhage.
Written by an international team of practitioners, this book offers an overview of the most important and common clinical issues in obstetrics and gynecology, including reproductive endocrinology, gynecologic oncology, and sexuality. It provides readers with current information on evidence-based approaches to the management of normal pregnancy, labor and birth, as well as the diagnosis, treatment, and prevention of high-risk pregnancy, infertility, and acute and chronic diseases in women of all ages. For each condition the authors give a clear definition, discuss its epidemiology, etiology and pathophysiology, and present the most recent protocols for its detection, screening, and clinical m...
Providing the latest evidence-based information on etiology, evaluation and treatment, this unique text provides an in-depth, comprehensive discussion of the epidemiology, genetic and endocrinologic factors and medical and surgical management of recurrent pregnancy loss (RPL). Taking a multidisciplinary approach including psychological treatment and patient perspectives, all aspects of current RPL prevention and treatment are elucidated. Detailed chapters provide real-world illustrative material and cover the set-up and management of RPL clinics and databases, containing practical tips. Recurrent Pregnancy Loss will be an excellent resource for OB-GYN specialists, general and reproductive endocrinologists, radiologists, hematologists, psychiatrists, psychologists, and any other investigators or clinicians treating patients confronted with this emotionally and physically trying condition.
This sensible book draws on evidence-based data, provides updated evidence focusing on the impact of pregnancy complications on long-term morbidity of both mother and child and aims to give a clear and comprehensive set of tools for general practitioners counseling women in different stages of their lives. Chapters are contributed by a multidisciplinary team of obstetricians, oncologists, pediatricians, internal medicine specialists, and psychiatrists. The book may serve as a valuable resource for a broad spectrum of clinicians and healthcare professionals. Medical and nursing students as well as residents in family medicine, obstetrics, and pediatrics may derive great benefit from it in various stages of their training.
“Wow. No one ever told me this!” Wendy Laura Belcher has heard this countless times throughout her years of teaching and advising academics on how to write journal articles. Scholars know they must publish, but few have been told how to do so. So Belcher made it her mission to demystify the writing process. The result was Writing Your Journal Article in Twelve Weeks, which takes this overwhelming task and breaks it into small, manageable steps. For the past decade, this guide has been the go-to source for those creating articles for peer-reviewed journals. It has enabled thousands to overcome their anxieties and produce the publications that are essential to succeeding in their fields. W...