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The Mongolian Gerbil Brain
The Mongolian gerbil brain lies in the anatomy of the blood vessels supplying blood to the brain. In all mammals, there is a special mechanism that compensates for the decreased blood flow to the brain in the case of development of stroke. This mechanism is missing in the gerbil and therefore makes the Mongolian gerbil a unique model for stroke. Dr. Mayevsky adopted the gerbil as a model for stroke and his laboratory uniquely studied the mitochondria in the gerbil brain under various pathophysiological conditions. This book describes the history of the Mongolian gerbil in research, the brain energy metabolism and mitochondrial function and brain real-time monitoring systems used in gerbils, as well as the brain vasculature of the Mongolian gerbil. Further, the book includes chapters on brain multisite recording under brain perturbations, multiparametric responses to brain activation, and the effect of neuroprotectants on the gerbil brain. This is an ideal book for research teams researching stroke and epilepsy.
Cortical Spreading Depression of Leao
This book focuses on energy metabolism and brain functions related to Cortical Spreading Depression of Leao (CSD), an important issue in brain pathophysiology. The first part of the book offers a comprehensive overview of the history and early research on CSD, and then discusses the recent advances in the technology used to map and monitor brain mitochondrial NADH redox state and other physiological functions during CSD. The chapters explore the connection between CSD and mitochondrial function under hypoxia, Ischemia and various drugs treatment, and provide a resource to scientists researching the development of CSD during various brain pathophysiological conditions. This book is essential to scientists and students working in the field of bioenergetics of the brain and various organs and tissues in the body. The use of this technology is also crucial and applicable in the neuroscience field.
Oxygen Transport to Tissue—IV
The International Society on OXygen Transport to Tissue (ISO'IT) has canpleted nine years as a society since its first fonnal meeting at Charleston-Clanson, South Carolina, United States of America in 1973. Prior to this time an active group of scientists and engineers rret in w::>rkshop environrrents, on a periodic basis, around the w::>rld. Meetings are ncM on an annual basis, alternating between Europe and the United States. The international gatherings include scientists and engineers in a variety of fields. ISOIT has produced a stable forum for the exchange of info:rmation on the rnicroenvirornnent of living cells, ranging fran the utilization of mathematics and engineering, through phy...
Oxygen Transport to Tissue XXV
The 30th scientific meeting of the International Society on Oxygen Transport to Tissue (ISOTT) was held at the Western Conference Centre, UMIST, Manchester, in August 2002. It was attended by some 96 delegates and accompanying persons and there were 128 presentations.
Brain Hypoxia-Ischemia Research Progress
Brain hypoxia-ischemia is a disorder characterised by a reduction in oxygen supply (hypoxia) combined with reduced blood flow (ischemia) to the brain. This condition may result from a localised obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ischemic attack, transient; brain infarction; brain oedema; coma; and other conditions. This book presents the latest research in this field from around the world.
Oxygen Transport to Tissue XI
The Ottawa '88 meeting of the International Society for Oxygen Transport to Tissue attracted a record number of participants and presentations. We were able to avoid simultaneous sessions and still keep the scientific program to four days by using poster sessions followed by plenary debate on each poster. To paraphrase the British physicist David Bohm, we tried to avoid an ordinary discussion, in which people usually stick to a relatively fixed position and try to convince others to change. This situation does not give rise to anything creative. So, we attempted instead to establish a true dialogue in which a person may prefer and support a certain point of view, but does not hold it nonnego...
Mitochondrial Function In Vivo Evaluated by NADH Fluorescence
This book covers both the technological development and biomedical applications of NADH fluorescence. Topics covered include perspectives on the history of monitoring NADH fluorescence, the relationship between mitochondrial function and other functions at the tissue level, responses of NADH to physiological and pathophysiological conditions, monitoring of NADH in the human brain and other organs, and metabolism. It also includes an in-depth look at flavoprotein (Fp) fluorescence and NADH in relation to redox state. This is an ideal book for biomedical engineers, researchers, and graduate students interested in learning the biomedical applications of NADH fluorescence. This book also: Covers...
