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Difficult Decisions in Thoracic Surgery
The complexity of decision making in thoracic surgery is growing exponentially. As new technology is introduced, physicians from nonsurgical specialties offer alternative and competing therapies for what was once the exclusive province of the thoracic surgeon. In addition, there is increasing knowledge regarding the efficacy of traditional thoracic surgical therapies. How to select among these varied and complex approaches is becoming increasingly difficult. The first two editions of this book have found wide acceptance among practicing surgeons, trainees, and educators. Chapters from them are regularly cited by the Thoracic Surgery Directors Association as valuable resources for their weekly curriculum exercises. As in the first two editions, chapters adhere to a specific format (updated for the third edition). This approach provides uniformity to the presentations, making it possible to identify useful material at a glance.
The Living Medicine
The fascinating and dramatic story of a forgotten, life-saving cure to conquer deadly bacterial infections - bacteriophages - and the remarkable scientists behind them When antibiotics started to fail the race to save humanity from deadly antibiotic resistant infections began. Science journalist Lina Zeldovich reveals the remarkable history of bacteriophages or 'phages', through the colourful lives of the British, French, Soviet and American scientists who discovered, developed and are now reviving this unique living medicine for seemingly incurable diseases. Starting with the original discovery of bacteriophages, or 'phages', in 1917, Zeldovich reveals how they were all but forgotten as ant...
Biopacemaking
The development of a bio-engineered pacemaker is of substantial clinical and also scientific interest because it promises to overcome several limitations of electronic pacemakers. Moreover it may answer the longstanding question of whether the complex structure of the sinus node is indeed a prerequisite for reliable pacemaking, or simpler structures might work as well. This book gives an overview of the current state-of-the-art of creating a bio-engineered pacemaker. It shows the approaches to develop of genetic and cell-based engineering methods suitable to implement them with safety and stability. It also illuminates the problems that need to be solved before bio-pacemaking can be considered for clinical use.
Thoracic Surgery in Children and Adolescents
The diagnosis and treatment of both congenital and acquired thoracic pathologies in children and adolescents require a high degree of specialization. This book provides practical guidelines for thoracic surgeons who operate on patients from neonatal age to adolescence and for pediatric surgeons who are challenged to treat disorders such as cystic malformations of the lung, mediastinal tumors, or chest wall deformities. The chapters, written by internationally acclaimed authors, include expert commentaries with tips and tricks for the clinical practice. Plus: QR codes for access to videos of surgical procedures.
Graft Preservation
Recently, solid organ transplant outcomes have benefited from improvements in graft preservation strategies. The use of ex vivo machine perfusion for organ has increased the donor pool and extended criteria for donor organs that would have previously been excluded from transplantation. Utilization of machine perfusion has protected donor organs from the injuries traditionally encountered by static cold storage, minimized rates of primary graft dysfunction, and even allowed for recovery of the function of marginal organs. Machine perfusion has also extended preservation periods well beyond what is considered acceptable after static cold storage for kidney, liver, lung, and hearts. The extende...
Tissue Engineering
Tissue engineering is a multidisciplinary field incorporating the principles of biology, chemistry, engineering, and medicine to create biological substitutes of native tissues for scientific research or clinical use. Specific applications of this technology include studies of tissue development and function, investigating drug response, and tissue repair and replacement. This area is rapidly becoming one of the most promising treatment options for patients suffering from tissue failure. This abundantly illustrated and well-structured guide serves as a reference for all clinicians and researchers dealing with tissue engineering issues in their daily practice.
Magnesium Alloys
Magnesium alloys usually have desirable properties including high chemical stability, easy processing and manufacturing, and also lightweight. Magnesium alloys weigh about 70% of aluminum alloy weight and 30% of iron and steel weight. Most of these alloys are used for fabrication of structures in aerospace industries. Magnesium belongs to the second main group of the periodic table of elements (alkaline earth metal) and therefore can't be found in pure state in nature and only exists as a chemical composition. This book collects new developments about magnesium alloys and their use in different industries.
Tissue Engineering
Features: Leading experts present their own most recent advances, Includes a wide spectrum of methods representing tissue engineering in many diverse disciplines, Supplies an understanding of diverse technologies and methods.
Minimally Invasive Cardiac Surgery: State of the art and current challenges
As a result of the significant progress in the development of emerging technologies and improved surgical techniques in the cardiovascular field, Minimally Invasive Cardiac Surgery (MICS) has undergone a rapid evolution over the past two decades. Currently, nearly half of all cardiac surgeries are performed through small skin incisions (minithoracotomy and ministernotomy), or involve other less-invasive approaches (no involvement of cardiopulmonary bypass, valve-sparing operations, etc.). This trend continues to evolve, notably with the development of increasingly efficient endoscopic, robotic and transcatheter procedures.
The Hepatocyte Review
It is thirty years since the technique of high-yield preparation of isolated hepatocytes, by collagenase perfusion of the liver, was published. The original method described by Berry and Friend has undergone many minor modifications by other workers, and the two-step procedure introduced by Seglen in 1976 has become the most frequent way to prepare hepatocyte suspensions. An important development introduced by Bissell in 1973 was the use of the cells as the first step in monolayer culture. The availability of the isolated hepatocyte preparation as cells in suspension or culture has undoubtedly facilitated research on the liver. This was emphasised in our book, published (with Dr. Greg Barrit...
