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Transmucosal Absorption Enhancers in the Drug Delivery Field
Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery systems that aim to address this issue. However, most proprietary delivery technologies that have progressed to clinical development are based on permeation enhancers (PEs) that have a history of safe use in man. This Special Issue entitled “Transmucosal Absorption Enhancers in the Drug Delivery Field” aims to present the current state-of-the-art in the application of PEs to improve drug absorption. Emphasis is placed on identification of novel permeation enhancers, mechanisms of barrier alteration, physicochemical properties of PEs that contribute to optimal enhancement action, new delivery models to assess PEs, studies assessing safety of PEs, approaches to assist translation of PEs into effective oral, nasal, ocular and vaginal dosage forms and combining PEs with other delivery strategies.
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Custom in Islamic Law and Legal Theory
This book explores the relationship between custom and Islamic law and seeks to uncover the role of custom in the construction of legal rulings. On a deeper level, however, it deals with the perennial problem of change and continuity in the Islamic legal tradition (or any tradition for that matter).
The Ocean of the Rivers of Story, Volume One
The name of Soma·deva's eleventh-century Ocean of the Rivers of Stories is no boast: in more than 20,000 verses it tells more than 250 tales. The reader has only to enjoy being swept away in the flood of stories, said to spring from that source of so much classical Indian literature, "The Long Story"--Publisher description.
Le défi social du développement. Globalisation et inégalités
Au tournant du millénaire, une équipe internationale de chercheurs s'est penchée sur la mondialisation et ses répercussions sur l'économie, la santé, l'éducation et la protection sociale. Une approche pluridisciplinaire et une analyse de plusieurs pays représentatifs leur ont permis ce constat : les inégalités perdurent et se renforcent même souvent, sous diverses formes et à des rythmes différents.
Deportation and the Confluence of Violence within Forensic Mental Health and Immigration Systems
The practices and technologies of evaluation and decision making used by professionals, police, lawyers and experts are questioned in this book for their participation in the perpetuation of historical forms of colonial violence through the enforcement of racial and eugenic policies and laws in Canada.
