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'This volume is an important step in furthering the discussion about how cluster strategies work and the implications for theory and policy.' – Jennifer Clark, Review of Regional Studies The role of innovations and clusters has increasingly dominated local and regional development policies in recent decades. This authoritative and accessible Handbook considers important aspects of high-tech clusters, analyses insightful cluster case studies, and provides a number of recommendations for cluster policies. The chapters in this Handbook are written by international experts in the field and present evidence of the scope, effects, and potential of clusters as concentrations of innovative activit...
Space is increasingly recognized as a legitimate factor that influences many processes and conceptual frameworks, including notions of spatial coherence and spatial heterogeneity that have been demonstrated to provide substance to both theory and explanation. The potential and relevance of spatial analysis is increasingly understood by an expanding sphere of cogent disciplines that have adopted the tools of spatial analysis. This book brings together major new developments in spatial analysis techniques, including spatial statistics, econometrics, and spatial visualization, and applications to fields such as regional studies, transportation and land use, political and economic geography, population and health. Establishing connections to existing and emerging lines of research, the book also serves as a survey of the field of spatial analysis and its links with related areas.
Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up to the pharmaceutical industry exciting opportunities in the field of new drug development. The series covers all of the above as well as the synthesis, testing and recording of the medicinal properties of natural products. - Describes the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - A valuable source for researchers in natural product and medicinal chemistry
This book covers recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; and many other relevant subjects, including new approaches to targeting proteolysis for therapy.
'the editors have done an excellent job in bringing together a comprehensive collection of cutting edge research findings on network theory. . .' - Sierdjan Koster, European Spatial Research and Policy
Yorkshire County Cricket Club is by far the most successful county cricket club in history. Since the County Championship was constituted in 1890, Yorkshire has, in addition to one shared Championship, won it outright on 30 occasions and Yorkshire cricket supporters take great pride in the county's cricketing history. As well as the club's successes, there have been 42 Yorkshire players chosen as Wisden Cricketers of the Year. Many have been world-class cricketers such as Wilfred Rhodes, Len Hutton, Fred Trueman and Geoffrey Boycott, with distinguished England careers. Many thousands of Wisden pages have been filled with Yorkshire cricket, Yorkshire cricketers and Tests in Yorkshire. Wisden ...
This book bridges the gap between economic theory and spatial econometric techniques. It is accessible to those with only a basic statistical background and no prior knowledge of spatial econometric methods. It provides a comprehensive treatment of the topic, motivating the reader with examples and analysis. The volume provides a rigorous treatment of the basic spatial linear model, and it discusses the violations of the classical regression assumptions that occur when dealing with spatial data.
Following theseminal Palgrave Handbook of Econometrics: Volume I , this second volume brings together the finestacademicsworking in econometrics today andexploresapplied econometrics, containing contributions onsubjects includinggrowth/development econometrics and applied econometrics and computing.
Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their uncontrolled proliferation and metastasis. There is now an increasing body of evidence demonstrating that the surrounding matrix and cell-matrix interactions are also major players in this process. Cells adhere and receive signals from various extracellular matrices via transmembrane receptors, the best known of which are the heterodimeric glycoproteins, integrins.
Key Features:First book of its kind in the fieldExamines and analyzes how key tools are used to conduct theoretical and empirical research in natural resource and environmental economics in contemporary timesCompiles various articles and accounts concerned with the relevant pedagogical discussionWritten by recognized experts and prominent international researchers in the field.