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This is the third and ?nal volume in a series of Lecture Notes based on the highlysuccessfulEuroSummerSchoolonExoticBeamsthathasbeenrunning yearly since 1993 (apart from 1999) and is planned to continue to do so. It is the aim of the series to provide an introduction to Radioactive Ion Beam (RIB) physics at the level of graduate students and young postdocs starting out in the ?eld. Each volume contains lectures covering a range of topics from nuclear theory to experiment to applications. Our understanding of atomic nuclei has undergone a major re-orientation over the past two decades and seen the emergence of an exciting ?eld of research: the study of ‘exotic’ nuclei. The availability of...
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This unique volume describes advances in the field of mechanochemistry, in particular the scaling up of mechanochemical processes. Scalable techniques employed to carry out solvent-free synthesis are evaluated. Comparability to continuous flow chemistry, the current industrial benchmark for continuous efficient chemical synthesis, is presented.The book concludes that mechanochemical synthesis can be scaled up into a continuous, sustainable process. It demonstrates that large-scale mechanochemistry can meet industrial demands, especially in the pharmaceutical industry. Features Mechanochemistry is rapidly developing as a multidisciplinary science on the borderline between chemistry, materials science and environmental science This unique text focuses on mechanochemistry with the ability to scale up and illustrates how mechanochemical synthesis is no longer an obstacle This timely book highlights recent advancements describing what can be achieved in chemical synthesis Mechanochemistry enables the synthesis of multiple polymorphic crystalline forms in the production of drugs in the form of tablets or granules in capsules
This book reviews current knowledge on the diagnosis and treatment (surgical and non-surgical) of cartilage defects at the knee joint. In the discussion of diagnosis, the focus is primarily on imaging findings, particularly those obtained with MRI. The remainder of the book is devoted to the full range of current conservative and surgical treatments, with attention to both treatment indications and results as reported in the recent literature. In reviewing non-surgical treatment, oral and intra-articular medical management is evaluated and rehabilitation and physical therapy are also considered. The three main types of surgical technique – microfracture surgery and similar procedures, mosaicplasty and related techniques, and autologous chondrocyte transplantation – are then extensively discussed in a series of highly informative chapters. This book will be of great practical value for clinicians, assisting in daily decision making.