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The Genetic Basis of Male Infertility
Every year there are new and exciting developments in assisted human reproduction, but how much do we really know about the underlying causes of infertility? This volume explores recent progress in the understanding of the genetics of spermatogenesis and male infertility. Topics include fundamental advances and current problems in the development and function of the testis, an outline of clinical findings in male infertility and an overview of the role of the Y chromosome in male fertility. Comprehensive critiques of posttranscriptional control during spermatogenesis, mammalian meiotic sterility, and comparative genetics of human spermatogenesis from the perspective of yeast, Drosophila and mice provide a global overview of the field.
International Review of Cytology
International Review of Cytology
The Male Germ Cell
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Fertility and Sterility: A Current Overview
This is the most complete and up-to-date medical reference work available on the newest clinical developments and scientific findings dealing with contraception, infertility, the endocrinology of reproduction, andrology, reproductive surgery, IVF technology, ethics, and research on human fertility and sterility. It contains 65 chapters by prominent international authorities. As the volume editors state in their Foreword, Whether you are a gynecologist, endocrinologist, biologist, andrologist, or basic scientist, or whatever your own interest-reproductive surgery, assisted medical procreation techniques, new drugs, contraception, reproductive endocrinology, or perhaps all of these-you will find that this book contains the appropriate answers.
Assisted Reproductive Technology
This text describes the rapid advances that have revolutionized reproductive medicine due to the result of converging and overlapping developments in reproductive biology, molecular biology and genetics.
Advances in Transport Phenomena
The term transport phenomena is used to describe processes in which mass, momentum, energy and entropy move about in matter. Advances in Transport Phenomena provide state-of-the-art expositions of major advances by theoretical, numerical and experimental studies from a molecular, microscopic, mesoscopic, macroscopic or megascopic point of view across the spectrum of transport p- nomena, from scientific enquiries to practical applications. The annual review series intends to fill the information gap between regularly published journals and university-level textbooks by providing in-depth review articles over a broader scope than in journals. The authoritative articles, contributed by internat...
Testis, Epididymis and Technologies in the Year 2000
A number of chapters present the most novel research on testicular and epididymal functions or on more general fields of hormone action and molecular cell biology as it is now a tradition. However, exceptionally, the book also contains several chapters dealing with the "Approaches and Tools in the Third Millenium". The unusual inclusion of technologies as such in the 2000 edition of the workshop was an absolute necessity, as these technologies are revolutionizing the fields of biology and medicine and, in many instances, how to do research. This volume gives the scientific community essential information about the very latest technical developments and their potential for future progress.
Sex-Based Differences in Lung Physiology
This book provides an overview of the latest experimental work on sex-based differences in lung function and inflammation. Readers will learn how these differences relate to individual predispositions for the development of lung disease in men and women, and in different stages of their reproductive lives. Further, the book focuses on diseases that predominantly affect women or men, with an emphasis on the physiological mechanisms underlying their pathobiology. In turn, these findings are complemented by chapters on recent studies, which investigate how circulating sex hormone levels impact the lung’s innate immune response to environmental agents and air pollution. The pathogeneses of asthma and viral respiratory infection are also major focus areas. As an outlook, the book also discusses current and future research directions aimed at developing sex-specific therapies for lung disease. To examine these anatomical and physiological differences in the male and female respiratory systems, the authors employ a broad range of methods from molecular and clinical biology. Accordingly, the book will be a fascinating read for physiologists and clinicians alike.
Cancer Cell Chemoresistance and Chemosensitization
"Despite the significant advances in cancer therapy made through constant evaluation and analysis of treatment aftereffects, the disease still remains one of the foremost causes of mortality worldwide killing more than 12 million people annually. The prime reason behind the failure of conventional chemotherapeutics which are used as the chief regimen in the comprehensive treatment of cancers is the development of chemoresistance. It can be either intrinsic or acquired and is primarily mediated via different key regulators like MDR, MAPK, NF-κB, PI3K/Akt, Wnt signaling pathways etc. Thus, agents which can target these regulatory elements or pathways and in turn sensitize cancer cells to chem...
Proteomics of Spermatogenesis
Recent developments of experimental techniques in cellular and molecular biology have made it possible to understand the molecular biology of male gametogenesis in greater detail. This book focuses on the description of specialized proteins, which are dominantly and/or specifically expressed in germ cells and localized in spermatozoa. There is an urgent need to classify proteins of spermatogenic cells with a view of their functions, and their applications in the regulation of fertility and in understanding infertility. The understanding of structural properties of male germ cell specific proteins can offer vulnerable points for targeted intervention in testis without generalized effects on stages of spermatogenesis. Besides targeted action in male germ cells, sperm specific proteins and polypeptides may also offer potential application in the development of a contraceptive vaccine.
