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Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set
Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic co...
Processing and Properties of Advanced Ceramics and Composites III
This book contains 17 papers from the Innovative Processing and Synthesis of Ceramics, Glasses and Composites and Advances in Ceramic Matrix Composites symposia held during the 2010 Materials Science and Technology (MS&T'10) meeting, October 17-21, 2010, Houston, Texas. Topics include: Fiber Composites; Modeling and Characterization; Nanomaterials; Testing; Microstructure-Property Relationships; Advanced Coatings; and Processing Methods.
Druggable Lipid Signaling Pathways
Lipids are responsible not just for constituting cellular membrane but also for storing energy, transducing signaling, and modifying proteins. Bioactive lipids, or lipid mediators, transduce signaling as intracellular messenger like phosphoinoitides, and also regulate cell-cell communication through G protein-coupled receptors (GPCRs) that are potentially valuable drug targets in many diseases. Until now, about 40 GPCRs within ~300 rhodopsin-like (class A) GPCRs, are identified as lipid GPCRs. Advances of lipid research have enabled to develop novel small molecules targeting lipid GPCRs for several diseases. Most notably, fingolimod (FTY720), a sphingosine 1-phosphate (S1P) receptor modulato...
Data Analytics-Based Demand Profiling and Advanced Demand Side Management for Flexible Operation of Sustainable Power Networks
This thesis deals with two important and very timely aspects of the future power system operation - assessment of demand flexibility and advanced demand side management (DSM) facilitating flexible and secure operation of the power network. It provides a clear and comprehensive literature review in these two areas and states precisely the original contributions of the research. The book first demonstrates the benefits of data mining for a reliable assessment of demand flexibility and its composition even with very limited observability of the end-users. It then illustrates the importance of accurate load modelling for efficient application of DSM and considers different criteria in designing ...
Nitric Oxide
Nitric oxide (NO) is a gas naturally found in the body that conveys information between cells. In the last decade researchers have found that NO is a signaling molecule of key importance for the cardiovascular system, regulating blood pressure and blood flow to different organs. In addition, discoveries surrounding nitric oxide's role as a principal neurotransmitter moderating erectile function, a pathophysiological negotiator and messenger in inflammation, and a weapon against infections have increased research attention across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology. - Edited by Nobel Laureate Louis J. Ignarro - Up-to-date therapeutic implications of nitric oxide research - Authored by world experts on nitric oxide - Detailed research of the biochemistry and synthesis of nitric oxide
ICT Innovations 2011
Information and Communication Technologies has enlarged its horizon and it is practiced under multidisciplinary contexts that introduce new challenges to theoretical and technical approaches. The most critical benefit of introducing new ICT technologies in our real world living are the new ways of working that the online world makes possible. Complexity, uncertainty and scaling issues of real world problems as well as natural phenomena in ecology, medicine and biology demanding ICT assistance create challenging application domains for artificial intelligence, decision support and intelligence systems, wireless sensor networks, pervasive and ubiquitous computing, multimedia information system...
Reviews of Environmental Contamination and Toxicology 194
Reviews of Environmental Contamination and Toxicology provides concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications. It covers all aspects of environmental contamination and associated toxicological consequences as well as facilitates the task of accessing and interpreting cogent scientific data.
Springer Handbook of Robotics
The second edition of this handbook provides a state-of-the-art overview on the various aspects in the rapidly developing field of robotics. Reaching for the human frontier, robotics is vigorously engaged in the growing challenges of new emerging domains. Interacting, exploring, and working with humans, the new generation of robots will increasingly touch people and their lives. The credible prospect of practical robots among humans is the result of the scientific endeavour of a half a century of robotic developments that established robotics as a modern scientific discipline. The ongoing vibrant expansion and strong growth of the field during the last decade has fueled this second edition o...
2D Functional Nanomaterials
2D Functional Nanomaterials Outlines the latest developments in 2D heterojunction nanomaterials with energy conversion applications In 2D Functional Nanomaterials: Synthesis, Characterization, and Applications, Dr. Ganesh S. Kamble presents an authoritative overview of the most recent progress in the rational design and synthesis of 2D nanomaterials and their applications in semiconducting catalysts, biosensors, electrolysis, batteries, and solar cells. This interdisciplinary volume is a valuable resource for materials scientists, electrical engineers, nanoscientists, and solid-state physicists looking for up-to-date information on 2D heterojunction nanomaterials. The text summarizes the sci...
