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Focusing on issues of gene organization, regulation, and evolution in the context of the whole life of the cell, this new volume complements the editors' classic 1993 volume Bacillus subtilis and Other Gram-Positive Bacteria. Building upon the previous edition, Bacillus subtilis and Its Closest Relatives contains an updated annotation of the complete B. subtilis genome and includes a unique compilation of major pathways of metabolism and macromolecular synthesis, correlating genes and proteins and assigning new functions to many genes. It also provides clear explanations of the major regulatory mechanisms that are unique to gram-positive bacteria as well as an overview of their special properties. This essential reference offers detailed, current information and is valuable reading for microbiologists, biotechnologists, and students.
Bacillus subtilis is a motile gram-positive bacterium widespread in the soil and the gut of animals which has been reported to cause opportunistic infections in immunocompromised patients. In Bacillus subtilis: Morphology, Functions and Role in Disease Management, the authors begin by outlining the main features of chemotaxis as a behaviour, then reviewing the molecular machinery Bacillus subtilis uses to sense and respond to chemical cues. Following this, the authors discuss how bacterial biofilms can form on biotic and abiotic surfaces, developing various reversible and irreversible stages depending on environmental conditions. An important characteristic of biofilm is the extracellular ma...
The Molecular Biology of the Bacilli, Volume I: Bacillus subtilis focuses on areas of research traditionally investigated in Bacillus subtilis, as well as topics in which outstanding progress has been made. It discusses the sporulation, defective bacteriophage, and transformation of Bacillus subtilis. Organized into 11 chapters, the book begins with the genetic map of Bacillus subtilis, followed by DNA replication and RNA polymerase of the said species. The book then describes the translational apparatus of Bacillus subtilis. It also explains the genetic transformation in Bacillus subtilis; the sporulation genes; the regulatory mechanisms in the development of lytic bacteriophages in this sp...
This book describes the structures and functions of active protein filaments, found in bacteria and archaea, and now known to perform crucial roles in cell division and intra-cellular motility, as well as being essential for controlling cell shape and growth. These roles are possible because the cytoskeletal and cytomotive filaments provide long range order from small subunits. Studies of these filaments are therefore of central importance to understanding prokaryotic cell biology. The wide variation in subunit and polymer structure and its relationship with the range of functions also provide important insights into cell evolution, including the emergence of eukaryotic cells. Individual cha...
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The genus Bacillw; has a long history of importance, both from an economic point of view and as a source of experimental microorganisms. This volume critically reviews aspects of identification, molecular biology, and growth that are of impor tance for the current and anticipated future exploitation of members of this group. In addition, the volume includes a chapter on taxonomy, as the importance of good taxonomy is often not fully appreciated; on sporulation, since so many important products are produced concomitantly with this process and we are beginning to understand the mechanisms by which the process is controlled; and, finally, on the cell envelope, as we are only just beginning to a...
Plant diseases are a serious threat to food production. This unique volume provides the fundamental knowledge and practical use of B.subtilis as a promising biocontrol agent. In order to replace chemical pesticides, one possibility is microbial pesticides using safe microbes. Bacillus subtilis is one of several candidates. Screening of the bacterium, the application of plant tests, clarification of its suppressive mechanism to plant pathogens and engineering aspects of suppressive peptides production are presented here. The author illustrates how B. subtilis is far more advantageous than, for example, Pseudomonas in biocontrol and can be considered as an useful candidate. Features: Bacterium B. subtilis suppresses many plant pathogens and is a biocontrol agent to replace chemical pesticides The book presents the bacterium's suppressive mechanism to plant pathogens, and engineering aspects of suppressive peptides production Biological control of plant disease plays an important role in sustainable agricultural production practices and is expected to replace agricultural chemicals
Bacillus subtilis has become widely adopted as a model organism for laboratory studies and is one of the best understood prokaryotes in terms of molecular and cellular biology. Its superb genetic amenability and relatively large size have provided powerful tools to investigate a bacterium in all possible aspects. This reference work provides a comprehensive and up-to-date analysis of the current knowledge and new research in Bacillus molecular and cellular biology. Subjects covered include chromosome replication, DNA repair, chromosome segregation, cell division, transcription and translation, RNA-mediated regulation, general and regulatory proteolysis, the actin-like MreB cytoskeleton, the membrane proteome, the cell wall, endospore formation, biofilms, multicellularity and social behaviour, competence and transformation.