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Medical Immunology
Maintaining the high standard of quality that made previous editions so successful, this totally revised and updated text incorporates the most recent advances in basic and clinical immunology-emphasizing diagnostic and clinical applications as well as state-of-the-art discussions of the principles and strategies for modulation of the immune response and treatment of hypersensitivity, autoimmune, and immune deficiency diseases. Includes clinical case studies as well as end-of-chapter questions-in the USML multiple choice format-for self-evaluation and preparation for licensure and specialty boards! Continuing as the only textbook providing a balanced discussion of basic and clinical immunolo...
Advances in Cancer Research
Advances in Cancer Research
Health Literacy in Clinical Research
Because of the individualized nature of drug and therapeutic treatments, clinical trials require participants who represent the diversity of the patient base. If early trials do not have a broad patient base, it can be difficult to know who may or may not benefit from or respond to a treatment later. In addition to diversity in recruitment, informed consent during participation is also crucial. If participants do not fully understand what they are signing up for, they may become confused, mistrustful, or drop out of a trial altogether, confusing investigators and possibly affecting the generalizability of a study. To explore the incorporation of health literacy practices into clinical trials...
Direct-to-Consumer Genetic Testing
Today, scores of companies, primarily in the United States and Europe, are offering whole genome scanning services directly to the public. The proliferation of these companies and the services they offer demonstrate a public appetite for this information and where the future of genetics may be headed; they also demonstrate the need for serious discussion about the regulatory environment, patient privacy, and other policy implications of direct-to-consumer (DTC) genetic testing. Rapid advances in genetic research already have begun to transform clinical practice and our understanding of disease progression. Existing research has revealed a genetic basis or component for numerous diseases, inc...
Institutional Review Board: Management and Function
Institutional Review Board (IRB) members and oversight personnel face challenges with research involving new technology, management of big data, globalization of research, and more complex federal regulations. Institutional Review Board: Management and Function, Third Edition provides everything IRBs and administrators need to know about efficiently managing and effectively operating a modern and compliant system of protecting human research subjects. This trusted reference manual has been extensively updated to reflect the 2018 revisions to the Federal Policy for the Protection of Human Subjects (Common Rule). An essential resource for both seasoned and novice IRB administrators and members, Institutional Review Board: Management and Function provides comprehensive and understandable interpretations of the regulations, clear descriptions of the ethical principles on which the regulations are based, and practical step-by-step guidance for effectively implementing regulatory oversight.
Promoting the “Human” in Law, Policy, and Medicine
Professor Bartha Maria Knoppers stepped down from the Canada Research Chair in Law and Medicine at McGill University in April 2024, a post she held for more than 20 years. Professor Knoppers consistently prioritized “humanity” in her academic work and in policymaking. As such, she forged a strong intellectual legacy, notably through her work on the human right to science, genomic and health-related data sharing, genome editing, human reproductive technologies, stem cell research, the rights of children, and population health. This collection of essays honours her extraordinary academic contributions to law, policy, and medicine.
Mental Capacity, Dignity and the Power of International Human Rights
Explores how society's privileging of autonomy and of civil and political freedoms, fails to uphold the human rights of those with cognitive disability.
COVID-19 and Education in Africa
With comprehensive examples from researchers across East Africa, West Africa, and Southern Africa, the book examines how primary, secondary, and tertiary education was affected by the pandemic and how its effects are shaping the future of education in Africa. This book addresses diverse issues relating to COVID-19 and education, including the gendered-, classed-, and disability-related effects of the pandemic; African educators’ and students’ experiences with different remote learning technologies; and the outcomes of government interventions in education, such as prolonged school closures. The chapters and case studies highlighted in the volume represent the voices of African educators, students, and parents as they share their experiences of the pandemic and their perspectives on how learning should be optimised to better manage future disruptions to education. This book is the first of its kind to comprehensively examine the effects of COVID-19 on education in Africa and will be essential reading for researchers, academics, and scholars of African education, international and comparative education, and education policy.
Perspectives on Research with H5N1 Avian Influenza
When, in late 2011, it became public knowledge that two research groups had submitted for publication manuscripts that reported on their work on mammalian transmissibility of a lethal H5N1 avian influenza strain, the information caused an international debate about the appropriateness and communication of the researchers' work, the risks associated with the work, partial or complete censorship of scientific publications, and dual-use research of concern in general. Recognizing that the H5N1 research is only the most recent scientific activity subject to widespread attention due to safety and security concerns, on May 1, 2012, the National Research Council's Committee on Science, Technology a...
Graft-vs.-Host Disease
With detailed contributions from more than 40 leading authorities on the topic, this Third Edition comprehensively explores the immunobiology, pathophysiology, and clinical manifestations of graft-versus-host disease (GVHD)-offering sections revealing the most up-to-date research on immune activation and dysregulation, the pathophysiology of target organ damage, and GVHD prevention and treatment.
