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Thermodynamics and Biophysics of Biomedical Nanosystems
This book highlights the recent advances of thermodynamics and biophysics in drug delivery nanosystems and in biomedical nanodevices. The up-to-date book provides an in-depth knowledge of bio-inspired nanotechnological systems for pharmaceutical applications. Biophysics and thermodynamics, supported by mathematics, are the locomotive by which the drug transportation and the targeting processes will be achieved under the light of the modern pharmacotherapy. They are considered as scientific tools that promote the understanding of physicochemical and thermotropic functionality and behavior of artificial cell membranes and structures like nanoparticulate systems. Therefore, this book focusses on new aspects of biophysics and thermodynamics as important elements for evaluating biomedical nanosystems, and it correlates their physicochemical, biophysical and thermodynamical behaviour with those of a living organism. In 2018, Prof. Demetzos was honored with an award by the Order of Sciences of the Academy of Athens for his scientific contribution in Pharmaceutical Nanotechnology.
New Developments in Mutation Research
Mutation refers to any change in the DNA of a cell. Mutations may be caused by mistakes during cell division, or they may be caused by exposure to DNA-damaging agents in the environment. Mutations can be harmful, beneficial, or have no effect. If they occur in cells that make eggs or sperm, they can be inherited; if mutations occur in other types of cells, they are not inherited. Certain mutations may lead to cancer or other diseases. This book gathers together and presents the latest research in this field.
The Emergence of Peptides and Dendrimers in Dentistry
This book provides detailed information about peptides and dendrimers and their application in dentistry. Modern peptide and dendrimer chemistry techniques are being used by dental researchers to identify, prevent, and possibly treat oral disorders. Even though the research on peptide chemistry and oral/dental health is still in its early stages, it has already yielded some promising findings that, if developed further, might have a positive impact on all of our health and help both sectors' research paradigms. The book was written for those interested in research on novel materials in the field of dentistry, and will open numerous doors for new research in the field of preventive dentistry.
Practical Guide to Studying Dendrimers
Dendrimers belong to the class of nanoparticles and are promising tools in nanomedicine. This book provides a compact, up-to-date description of methods useful in studying biological properties of dendrimers. It focuses on biological properties of dendrimers and creates a practical guide that reviews the methods used to study these aspects of dendrimers. There is a need to describe a set of methods applied to characterise different types of dendrimers. Such standardisation will hopefully help to compare different families of dendrimers in the future. This book presents a methodological approach and provides useful tips how to study dendrimers.
Dendrimers in Biomedical Applications
This book will provide comprehensive coverage of dendrimer applications and clear indications for future research. It will appeal to chemists, biologists and materials scientists, working in both academia and industry.
Bibliographic Index
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Characterisation of Drug Nanocarriers
Nanotechnology has the potential to solve many unmet, urgent healthcare requirements. However, bridging the translational gap between lab and clinic for nanodrugs is still challenging, and there is limited guidance on regulatory-relevant information and approaches. The main aim of this book is to provide guidance on characterization of drug carrier properties and efficacy required for regulatory acceptance of nanomaterials for their use in medicine.This book provides a comprehensive overview of drug loading and delivery nanocarriers, including their characteristics, methodologies and techniques to evaluate the association and interaction of the drug with different nanocarriers.
Smart Systems in Biotechnology
This compact volume is focused on an eclectic mix of biotechnological and biomedical applications of stimuli-sensitive polymeric materials. It starts with their chemical synthesis and design strategies. This is followed by discussions of their applications in microfluidics, biosensors, wound healing and anticancer therapy. Two other interesting applications covered are the design of aptamer-based smart surfaces for biological applications and use of smart hydrogels in tissue engineering. In general, it provides a snapshot of the current state-of-the-art in design and applications of smart systems at the interfaces of biological sciences.
Nanotechnologies for Solubilization and Delivery in Foods, Cosmetics and Pharmaceuticals
Beginning with the basics of surfactant chemistry and micellization, this book presents a range of nanotechnology strategies for controlling colloidal and polymeric structures for the solubilization and targeted delivery of food nutrients and pharmaceuticals.
Biophysics and Structure to Counter Threats and Challenges
This ASI brought together a diverse group of experts who span virology, biology, biophysics, chemistry, physics and engineering. Prominent lecturers representing world renowned scientists from nine (9) different countries, and students from around the world representing eighteen (18) countries, participated in the ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU). The central hypothesis underlying this ASI was that interdisciplinary research, merging principles of physics, chemistry and biology, can drive new discovery in detecting and fighting chemical and bioterrorism agents, lead to cleaner environments and improved energy sources, and help propel development in NATO partner countries. At the end of the ASI students had an appreciation of how to apply each technique to their own particular research problem and to demonstrate that multifaceted approaches and new technologies are needed to solve the biological challenges of our time. The course succeeded in training a new generation of biologists and chemists who will probe the molecular basis for life and disease.
