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Tumour Viruses
This book is a printed edition of the Special Issue "Tumour Viruses" that was published in Viruses
Autophagy Dysfunction in Alzheimer's Disease and Dementia
Autophagy Dysfunction in Alzheimer’s Disease and Dementia provides an overview for researchers and clinicians on the mechanisms involved in protein degradation in Alzheimer’s. The book discusses the implication of autophagy dysfunction in these diseases and how it causes degenerated proteins, including aggregated tau and aggregated amyloid protein. Other sections explores the possibilities of potential drug development through autophagy modulation, making this a great resource on the study of how autophagy dysfunction has been linked to the accumulation of misfolded proteins that cause death of neurons in Alzheimer’s and other neurodegenerative diseases. Discusses the implication of autophagy dysfunction in neurodegenerative diseases Highlights the mechanisms involved in protein degradation Explores the possibilities of drug development through autophagy modulation
Cognitive Models in Language and Thought
The volume offers a number of representative papers on cognitive models that are invoked when people deal with questions of social identity, political and economic manipulation, and more general issues such as the genomic discourse. In line with the well-known volume Cultural Models in Language and Thought by Holland and Quinn (1987), the volume shows that Cognitive Linguistics has further explored the idea that we think about social reality in terms of models - 'cognitive/cultural models' or 'folk theories'. As in cultural models, the present volume demonstrates that the technical apparatus of Cognitive Linguistics can be used to analyze the various ways our conception of social reality is shaped by underlying cognitive and/or cultural models or patterns of thought, and also looks into how this is done. The new inroad the volume wants to pursue is the deliberate and explicit orientation towards a cognitive sociolinguistics, or more generally, a cognitive semiotics.
Hollands goud
Athene 2004, kippenvel. Wielrenster Leontien Zijlaard-van Moorsel valt, maar sluit haar olympische carrière af met goud. Tokio 1964: zwaar teleurgestelde en huilende Japanners omdat Anton Geesink de judowereld op zijn kop zet en goud wint. Sydney 2000: Pieter van den Hoogenband is op de 100 meter vrij, het koningsnummer, 0,06 seconden sneller dan zijn geduchte tegenstander. Hij kan het zelf nauwelijks geloven. In Hollands goud laat Wilfred van Buuren de lezer hun wedstrijden, en die van alle andere Nederlandse gouden topsporters, opnieuw beleven. Wie was de eerste Nederlandse winnaar met een gouden medaille, waarom haalden we bij de Spelen van 1960 geen goud en hoe vaak deed Van den Hoogenband mee? Wanneer deden er überhaupt voor het eerst Nederlanders mee? In Hollands goud alle verhalen en feiten van Nederlandse goudwinnaars op een rij.
Frans Hals
Frans Hals is one of the most important portrait painters of all time. Like Rembrandt, the famous Dutch Baroque master's striking portraits of the bourgeoisie and social outsiders are distinguished by their extraordinary vividness and accurate depiction. His sketch-like paintings, executed with bold brushstrokes, had a decisive influence on modernist painting. This comprehensive publication coincides with the first major survey exhibition of Hals' oeuvre in more than thirty years. FRANS HALS (1582/84–1666) was born in Antwerp, the son of a cloth merchant. In 1610 he was accepted into the Haarlem Guild of St. Luke. Hals created hundreds of genre paintings, individual, and group portraits and enjoyed great public prestige. Despite his fame during his lifetime, it was not until the nineteenth century that he was enthusiastically rediscovered by the Impressionists and Realists.
Jan Wils
Overzicht van het werk van de Nederlandse architect (1891-1972), voorzien van een oeuvrecatalogus en enkele artikelen en essays van zijn hand.
