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Sex differences and cardiovascular therapeutics
Scientific evidence from both preclinical, and clinical studies indicates that male and female patients with cardiovascular disease (CVD) exhibit different clinical, epidemiological, and pathological characteristics, with sexually dimorphic biological factors exhibiting a significant influence in the development of CVD and therapeutic responses. Sexually dimorphic physiology that contributes to sex differences in cardiovascular therapeutic responses may include; immune responses, cardio-renal health, the blood-brain barrier, coronary atherosclerosis pathology, complications of COVID-19 infections, and the interplay between psychological factors and sedentarism. Furthermore, current knowledge...
Therapeutics in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) continues to be a condition associated with a high morbidity and mortality despite the advances in treatment strategies over the past 25 years. Although defined by strict hemodynamic criteria, PAH is a syndrome based on diverse etiologies and pathogenesis. PAH is characterized by excessive pulmonary vascular remodeling, pulmonary arterial obstruction and elevated pulmonary vascular resistance (PVR), which result in a marked increase in right ventricle (RV) afterload. Eventually, the RV is not able to cope with the increased load and HF develops.
Insights in Healthcare Professions Education: 2022
We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Healthcare Profession Educations. Frontiers has organized a series of Research Topics to highlight the latest advancements in science in order to be at the forefront of science in different fields of research. This editorial initiative of particular relevance, led by Dr. Jacqueline Bloomfield and Lynn Monrouxe, Specialty Chief Editors of the Healthcare Professions Education section, is focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of Healthcare Professions Education.
Community Development for Social Change
Community Development for Social Change provides a comprehensive introduction to the theory and practice of community development and associated activities, discusses best practice from global experience and links that to the UK context. The book integrates the realities of practice to key underpinning theories, human rights, values and a commitment to promoting social justice. A range of practice models are described and analysed, including UK models, popular education and community organising, as well as a range of practice issues that need to be understood by community development workers. For example, strategies to promote individual and community empowerment, challenging discrimination,...
