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How Tobacco Smoke Causes Disease
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
The Molecular Biology of the Bacilli
The Molecular Biology of the Bacilli: Volume II is a collection of material relevant to the basic knowledge of the bacillus system and to the development of the bacillus system for industrial applications. This volume presents bacillus research studies on the unique characteristics of bacilli and its interesting comparisons with other bacteria, specifically Escherichia coli. The first four chapters focus on the Bacillus subtilis, specifically the translational specificity, DNA repair, chemotaxis, and sporulation. Chapter 5 discusses the protoplast fusion in bacillus while Chapter 6 delves on the secretion of proteins by bacilli. Chapter 7 explores the function of bacilli as insecticide. Bacillus thuringiensis is also mentioned in this chapter. This topic is further discussed in Chapter 8 where the genetics and molecular biology of B. thuringiensis are discussed. This volume aims to be of help to students and researchers in various fields of biochemistry, genetics, biological sciences, and microbiology.
DNA Damage and Repair
The First International Congress on DNA Damage and Repair was held in Rome, Italy, July 12-17, 1987. It was organized by the Italian Com mission for Nuclear Alternative Energy Sources. The subject of DNA damage and repair involves almost all the fields ofbidogical sciences. Some of the more prominent ones include carcino genesis, photobiology, radiation biology, aging, enzymology, genetics, and molecular biology. These individual fields have their own interna tional meetings and although the meetings often have sessions devoted to DNA repair, they do not bring together a wide diversity of international workers in the field to exchange ideas. The purpose of the Congress was to facilitate such...
DNA Damage Recognition
Stands as the most comprehensive guide to the subject-covering every essential topic related to DNA damage identification and repair. Covering a wide array of topics from bacteria to human cells, this book summarizes recent developments in DNA damage repair and recognition while providing timely reviews on the molecular mechanisms employe
DNA Damage, DNA Repair and Disease Volume 1
The overall aim of this book is to give scientists in academia and industry a comprehensive overview of the field of DNA damage and DNA repair and related human diseases.
The Biochemistry of the Nucleic Acids
When the first edition of this book was published in 1950, it predated the publication of the double-helical structure of DNA by three years. It is not, therefore, surprizing that nothing of the original book remains in the current edition. Indeed, such is the pace of change in the field of nucleic acids that less than 50% of material incorporated into the 1986 edition has been retained. The book aims at the advanced undergraduate and at graduates that are undertaking course work or requiring an in-depth background for their research. It also aims to provide the established scientist with a single text that permits updating across the whole field from DNA structure, replication and repair, through gene expression and its control to protein synthesis. Every chapter is accompanied by thorough referencing that enables the reader to evaluate personally the data and methodology that cannot be included in the text. In an attempt to keep this list within bounds, references are limited to about ten per page and, to accommodate the more recent literature, many of the older references have been left out in this latest edition.
