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Phytates in Cereals and Legumes
This timely publication brings together into a single volume an overview of the extensive published data on cereal and legume phytates. It presents important information regarding historical background, physiological functions, and uses. Biosynthesis and dephosphorylation, phytase enzyme, and methods for analysis are covered. Also included is invaluable information on occurrence, distribution, content, and dietary intake; and interactions with minerals, proteins, carbohydrates and enzymes. Digestion and bioavailability, nutritional consequences, and technologies for removal of phytates from cereals and legumes are discussed. There are numerous tables and illustrations included. This volume is indispensable for researchers and food scientists in phytate research and the technology/processing of cereals and legumes.
α–Gal and Anti–Gal
Uri Galili who originally discovered anti-Gal and the unique evolution of &agr;-1,3-galactosyltransferase, and by Dr. Jose-Luis Avila who has been studying anti-Gal significance in Chagas' disease and in Leishmania infections. This book covers the main areas of research on &agr;-1,3galactosyltransferase, its product the &agr;-gal epitope (Gal&agr;1-3Gal&bgr;1-4GlcNAc-R) and the natural anti-Gal antibody that interacts with this epitope
Fusion of Biological Membranes and Related Problems
Membrane fusion and targeting processes are tightly regulated and coordinated. Dozens of proteins, originating from both the cytoplasm and membranes are involved. The discovery of homologous proteins from yeast to neurons validates a unified view. Although much is known about the interfering proteins, the events occurring when two lipid bilayers actually fuse are less clear. It should be remembered that lipid bilayers behave like soap-bubbles fusing when meeting each other. In this respect interfering proteins should be considered as preventing undesirable and unnecessary fusion and eventually directing the biological membrane fusion process (when, where, how, and overcoming the activation energy). In this latest volume in the renowned Subcellular Biochemistry series, some aspects of fusion of biological membranes as well as related problems are presented. Although not complete, there is a lot of recent information including on virus-induced membrane fusion. The contributors of the chapters are all among the researchers who performed many of the pioneering studies in the field.
Adaptive Soil Management : From Theory to Practices
The book focuses in detail on learning and adapting through partnerships between managers, scientists, and other stakeholders who learn together how to create and maintain sustainable resource systems. As natural areas shrink and fragment, our ability to sustain economic growth and safeguard biological diversity and ecological integrity is increasingly being put to the test. In attempting to meet this unprecedented challenge, adaptive management is becoming a viable alternative for broader application. Adaptive management is an iterative decision-making process which is both operationally and conceptually simple and which incorporates users to acknowledge and account for uncertainty, and sus...
Membrane Dynamics and Domains
The fluid-mosaic model of membrane structure formulated by Singer and Nicolson in the early 1970s has proven to be a durable concept in terms of the principles governing the organization of the constituent lipids and proteins. During the past 30 or so years a great deal of information has accumulated on the composition of various cell membranes and how this is related to the dif ferent functions that membranes perform. Nevertheless, the task of explaining particular functions at the molecular level has been hampered by lack of struc tural detail at the atomic level. The reason for this is primarily the difficulty of crystallizing membrane proteins which require strategies that differ from th...
Cholesterol
Experts investigate the biochemical and biomedical aspects of cholesterol, addressing its metabolism in normal and disease states. They discuss a broad range of topics, including key steps in the cholesterol biosynthetic pathway, and the role of cholesterol in cancer, atherosclerosis, and diseases of the nervous system. The book's comprehensive coverage also includes the pathological consequences and potential therapies for various disease states, and the development of new anti-atherogenic drugs.
Fat-Soluble Vitamins
The subject for a volume on the fat-soluble vitamins needs no justification considering the importance of this group of nutrients and the rate of expan sion of our knowledge of its role in cell biology, genetics, and disease. The level of our understanding has clearly moved from knowing what fat soluble vitamins do to how they perform their functions. Hand in hand with a knowledge of their molecular mechanisms of action is the recognition that vitamins are used sparingly, and regeneration processes operate in certain cases to recycle vitamins from their metabolites. We have divided the volume into alphabetical sections beginning with vitamin A and the carotenoids through vitamins D, E, F, and K, and ending with coenzyme Q. The contributors are all acknowledged experts in their particular fields and have made significant contributions to published research results. All have worked assiduously to deliver the product of their labors on a restricted time scale and to provide the most up-to date information on their respective topics. We are truly grateful for their indulgence.
Cyclitols and Phosphoinositides
Cyclitols and Phosphoinositides covers the proceedings of the 1977 Conference on Cyclitols and Phosphoinositides, held at the Kellogg Center for Continuing Education, Michigan State University, East Lansing, Michigan. This book is organized into eight parts encompassing 43 chapters. The first parts describe the chemistry of cyclitols, inositol phosphates, and phosphoinositides. The subsequent parts explore the ubiquitous myoinositol and its phospholipids in animals, plants, yeast, bacteria, and molds; in various body parts, such as iris, brain, nerves, pineal, testis, lymphocytes, pancreas, parotid, retina, synapses, lysosomes; and the test tube. The last parts consider the mechanism of inositol biosynthesis and the meaning of increased phosphatidylinositol turnover in response to extracellular stimuli. This book will prove useful to research workers in the fields of organic chemistry, biochemistry, genetics, physiology, microbiology, pharmacology, botany, and nutrition.
