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Deciphering anatomical and functional maps in the nervous system is a main challenge for both clinical and basic neuroscience. Modern approaches to mark and manipulate neurons are bringing us closer than ever to better understand nervous system wiring diagrams. Here we present both original research and review material on current work in this area. Together, this eBook aims to provide a comprehensive snapshot of some of the tools and technologies currently available to investigate brain wiring and function, as well as discuss ongoing challenges the field will be confronted with in the future.
This volume seeks to familiarize readers with a diverse range of technologies and approaches for probing neuron and circuit architecture, and, when possible, to attach detailed protocols to help guide readers toward practical application. From classical lipophilic dye and conjugated lectin tracing techniques, to electrophysiological, in vivo imaging, viral tract tracing, and emerging genetic methods to mark, manipulate, and monitor neural circuits, Neural Tracing Methods: Tracing Neurons and Their Connections includes reference to an arsenal of tools and technologies currently being implemented in model systems ranging from flies to mice. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.Essential and authoritative, Neural Tracing Methods: Tracing Neurons and Their Connections collects a comprehensive compilation of chapters authored by inventors and expert users, that describes state-of-the-art neuronal tracing and functional analysis methods in order to aid researchers in continuing this vital pathway of study.
Publisher’s note: In this 2nd edition, the following article has been added: “Editorial: Involvement of Bioactive Peptides in the Control of Cell Survival, Proliferation and Plasticity in Physiological and Pathological Conditions”
This book provides applications for the revolutionary technique of optogenetics, which combines genetic and optical methods to observe the function of neurons.
Current pharmacotherapies and surgical intervention provide limited benefit in the treatment of neural injuries or halting disease progression and has resulted in significant hope for the successes of stem cell research. The properties of stem cells render them appropriate for cell replacement therapy, endogenous repair, disease modeling as well as high-throughput drug screening and development. Such applications will aide in increasing our knowledge and developing treatments for neurodegenerative disorders such as Parkinson’s disease and Huntington’s diseases as well as neural traumas including ischemic brain damage and traumatic brain injury. This Frontiers Research topic encouraged co...
Peterson's Graduate Programs in Genetics, Developmental Biology, & Reproductive Biology; Marine Biology; and Microbiological Sciences contains a wealth of information on universities that offer graduate/professional degrees in these fields that include Genomic Sciences, Human Genetics, Molecular Genetics, Teratology, Bacteriology, Immunology, Infectious Diseases, Medical Microbiology, and Virology. Up-to-date data, collected through Peterson's Annual Survey of Graduate and Professional Institutions, provides valuable information on degree offerings, professional accreditation, jointly offered degrees, part-time and evening/weekend programs, postbaccalaureate distance degrees, faculty, studen...
Peterson's Graduate Programs in the Biological Sciences 2012 contains a wealth of information on accredited institutions offering graduate degree programs in these fields. Up-to-date data, collected through Peterson's Annual Survey of Graduate and Professional Institutions, provides valuable information on degree offerings, professional accreditation, jointly offered degrees, part-time and evening/weekend programs, postbaccalaureate distance degrees, faculty, students, requirements, expenses, financial support, faculty research, and unit head and application contact information. There are helpful links to in-depth descriptions about a specific graduate program or department, faculty members and their research, and more. There are also valuable articles on financial assistance, the graduate admissions process, advice for international and minority students, and facts about accreditation, with a current list of accrediting agencies.