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Towards a New 3Rs Era in Experimental Research
With the persisting need of animal experimentation for fundamental and applied research, the relevance and importance of the 3Rs Principle cannot be ignored. The 3Rs Principle was put forward over 50 years ago, providing an essential framework for more humane animal experimentation in research. In this half-century the research landscape within which this principle is applied has dramatically changed and evolved, with ever more emerging venues to explore for 3Rs advancement and implementation.
EBOOK: A Sociology of Mental Health and Illness
How do we understand mental health problems in their social context? A former BMA Medical Book of the Year award winner, this book provides a sociological analysis of major areas of mental health and illness. The book considers contemporary and historical aspects of sociology, social psychiatry, policy and therapeutic law to help students develop an in-depth and critical approach to this complex subject.New developments for the fifth edition include: Brand new chapter on prisons, criminal justice and mental health Expanded coverage of stigma, class and social networks Updated material on the Mental Capacity Act, Mental Health Act and the Deprivation of Liberty A classic in its field, this we...
Investment Psychology Explained
Expert advice in a back-to-basics handbook on how to beat the market-the classic way In Investment Psychology Explained Martin J. Pring, one of the most respected independent investment advisors in the world, argues that in the revisionist '90s there are no quick, magical paths to market success. Rather, he emphasizes the timeless values of hard work, patience, and self-discipline-and much more. Drawing on the wisdom of creative investors such as Jesse Livermore, Humphrey Neill, and Barnard Baruch, as well as his own experience, Pring shows how to: * Overcome emotional and psychological impediments that distort decision making * Map out an independent investment plan-and stick to it * Know w...
Capital Ideas
Capital Ideas traces the origins of modern Wall Street, from the pioneering work of early scholars and the development of new theories in risk, valuation, and investment returns, to the actual implementation of these theories in the real world of investment management. Bernstein brings to life a variety of brilliant academics who have contributed to modern investment theory over the years: Louis Bachelier, Harry Markowitz, William Sharpe, Fischer Black, Myron Scholes, Robert Merton, Franco Modigliani, and Merton Miller. Filled with in-depth insights and timeless advice, Capital Ideas reveals how the unique contributions of these talented individuals profoundly changed the practice of investment management as we know it today.
Language and the Declining World in Chaucer, Dante, and Jean de Meun
Medieval commentaries on the origin and history of language used biblical history, from Creation to the Tower of Babel, as their starting-point, and described the progressive impairment of an originally perfect language. Biblical and classical sources raised questions for both medieval poets and commentators about the nature of language, its participation in the Fall, and its possible redemption. John M. Fyler focuses on how three major poets - Chaucer, Dante, and Jean de Meun - participated in these debates about language. He offers fresh analyses of how the history of language is described and debated in the Divine Comedy, the Canterbury Tales and the Roman de la Rose. While Dante follows the Augustinian idea of the Fall and subsequent redemption of language, Jean de Meun and Chaucer are skeptical about the possibilities for linguistic redemption and resign themselves, at least half-comically, to the linguistic implications of the Fall and the declining world.
De Sphaera of Johannes de Sacrobosco in the Early Modern Period
This open access book explores commentaries on an influential text of pre-Copernican astronomy in Europe. It features essays that take a close look at key intellectuals and how they engaged with the main ideas of this qualitative introduction to geocentric cosmology. Johannes de Sacrobosco compiled his Tractatus de sphaera during the thirteenth century in the frame of his teaching activities at the then recently founded University of Paris. It soon became a mandatory text all over Europe. As a result, a tradition of commentaries to the text was soon established and flourished until the second half of the 17th century. Here, readers will find an informative overview of these commentaries comp...
Multiple Sclerosis Therapeutics
This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.
