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Vitamin B 12 and B 12-Proteins
This timely and topical book reviews the important developments in the 'B12-field' with regard to biological, chemical, pharmaceutical and medicinal aspects. In over 30 chapters the approx. 100 internationally renowned authors give deeper insight into the prospering research activites around B12. This book is a must for everybody who works with or on vitamins and porphyrine (-like) ring systems. Topics of particular interest include: Biosynthesis of Vitamin B12; B12-catalyzed enzymatic reactions and their mechanisms; structural B12-chemistry; reactivity of B12 and B12-models; structure and function of B12-proteins; metabolic transport and storage of B12; pathological effects of B12-deficiency.
Redox-Active Ligands
Redox-Active Ligands Authoritative resource showcasing a new family of ligands that can lead to better catalysts and promising applications in organic synthesis Redox-Active Ligands gives a comprehensive overview of the unique features of redox-active ligands, describing their structure and synthesis, the characterization of their coordination complexes, and important applications in homogeneous catalysis. The work reflects the diversity of the subject by including ongoing research spanning coordination chemistry, organometallic chemistry, bioinspired catalysis, proton and electron transfer, and the ability of such ligands to interact with early and late transition metals, lanthanides, and a...
Successful Drug Discovery, Volume 4
Provides unique insider insight into the current drug development process, and what it takes to achieve success In this fourth volume in the series, inventors and primary developers of drugs that made it to the market continue telling the story of the drugs? discovery and development, and discuss the sometimes twisted route from the first drug candidate molecule to the final marketed one. Beginning with a general section addressing overarching topics for drug discovery, the book offers seven chapters that feature selected case studies describing recently introduced drugs or drug classes. These include small molecule drugs as well as biopharmaceuticals and range across different therapeutic f...
Chemistry and Biochemistry of B12
A Definitive New Reference for the Latest Advances in B_12 Chemistry and Biochemistry Over the past decade, the field of B_12 research has been revolutionized by such major breakthroughs as the unraveling of the entire biosynthetic pathway for this important vitamin. This comprehensive compendium surveys the wealth of information that has accumulated, covering in one volume virtually all aspects of the field-from physical and inorganic chemistry to enzymology, microbiology, medicine, and diagnostic and therapeutic applications. Edited by Dr. Ruma Banerjee, a highly respected and active member of the B_12 community, this work provides B_12 researchers with a dependable and up-to-date referenc...
The Organic Chemistry of Biological Pathways
Intended for advanced undergraduates and graduate students in all areas of biochemistry, The Organic Chemistry of Biological Pathways provides an accurate treatment of the major biochemical pathways from the perspective of mechanistic organic chemistry.
Environmental Chemistry, Eighth Edition
Environmental Chemistry, Eighth Edition builds on the same organizational structure validated in previous editions tosystematically develop the principles, tools, and techniques of environmental chemistry to provide students and professionals with a clear understanding of the science and its applications. Revised and updated since the publication of the best-selling Seventh Edition, this text continues to emphasize the major concepts essential to the practice of environmental science, technology, and chemistry while introducing the newest innovations to the field. The author provides clear explanations to important concepts such as the anthrosphere, industrial ecosystems, geochemistry, aquat...
Handbook on Clostridia
Clostridia is one of the largest bacterial genera with an enormous potential for biotechnical and medical applications. Despite growing scientific, medical, and industrial interest, information on basic methods, biochemical fundamentals, clinical practice, industrial applications, and novel developments remains scattered in a variety of research ar
