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Vitamin B 12 and B 12-Proteins
This timely and topical book reviews the important developments in the 'B12-field' with regard to biological, chemical, pharmaceutical and medicinal aspects. In over 30 chapters the approx. 100 internationally renowned authors give deeper insight into the prospering research activites around B12. This book is a must for everybody who works with or on vitamins and porphyrine (-like) ring systems. Topics of particular interest include: Biosynthesis of Vitamin B12; B12-catalyzed enzymatic reactions and their mechanisms; structural B12-chemistry; reactivity of B12 and B12-models; structure and function of B12-proteins; metabolic transport and storage of B12; pathological effects of B12-deficiency.
Organic Reacty Physical & Biol Aspects SP 148
Organic Reactivity provides a timely account of the current state of research at the interface between physical organic and bio-organic chemistry. It bridges the gap between physical and biological aspects of organic chemistry, introducing physical organic chemists to new mechanistic problems in biology, and encouraging a more rigorous mechanistic approach in bio-organic chemists. It demonstrates the relevance of new thinking in physical organic chemistry to bio-organic chemists, drawing upon a variety of current mechanistic themes. Organic Reactivity is an extremely important source book for lecturers keen to steer students towards highly relevant, contemporary research, and to show where different areas of chemistry, often perceived as exclusive, interlink and have common principles. It also provides laboratory chemists with pointers to new directions in research.
Molecular Mechanisms in Bioorganic Processes
The proceedings and lectures from an international symposium on molecular mechanisms and bio-organic processes held at the University of Newcastle-Upon-Tyne, July 1989. Current topics relevant to the title of the symposium are addressed by chemists, biochemists and medical scientists.
Successful Drug Discovery, Volume 4
Provides unique insider insight into the current drug development process, and what it takes to achieve success In this fourth volume in the series, inventors and primary developers of drugs that made it to the market continue telling the story of the drugs? discovery and development, and discuss the sometimes twisted route from the first drug candidate molecule to the final marketed one. Beginning with a general section addressing overarching topics for drug discovery, the book offers seven chapters that feature selected case studies describing recently introduced drugs or drug classes. These include small molecule drugs as well as biopharmaceuticals and range across different therapeutic f...
Handbook on Clostridia
Clostridia is one of the largest bacterial genera with an enormous potential for biotechnical and medical applications. Despite growing scientific, medical, and industrial interest, information on basic methods, biochemical fundamentals, clinical practice, industrial applications, and novel developments remains scattered in a variety of research ar
Special Reports
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Chemistry and Biochemistry of B12
A Definitive New Reference for the Latest Advances in B_12 Chemistry and Biochemistry Over the past decade, the field of B_12 research has been revolutionized by such major breakthroughs as the unraveling of the entire biosynthetic pathway for this important vitamin. This comprehensive compendium surveys the wealth of information that has accumulated, covering in one volume virtually all aspects of the field-from physical and inorganic chemistry to enzymology, microbiology, medicine, and diagnostic and therapeutic applications. Edited by Dr. Ruma Banerjee, a highly respected and active member of the B_12 community, this work provides B_12 researchers with a dependable and up-to-date referenc...
