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Ketamine
The emergence of ketamine--previously known as a combat anesthetic and club drug--as a treatment for depression. Ketamine, approved in 2019 by the Food and Drug Administration for the treatment of depression, has been touted by scientists and media reports as something approaching a miracle cure. This volume in the MIT Press Essential Knowledge series chronicles the ascent of a drug that has been around for fifty years--in previous incarnations, a Vietnam-era combat anesthetic and a popular club drug--that has now been reinvented as a treatment for depression. Bita Moghaddam, a leading researcher in neuropharmacology, explains the scientific history and the biology of ketamine, its clinical use, and its recently discovered antidepressant effects, for the nonspecialist reader.
Neurobiology of Mental Illness
The new edition of this definitive textbook reflects the continuing reintegration of psychiatry into the mainstream of biomedical science. The research tools that are transforming other branches of medicine - epidemiology, genetics, molecular biology, imaging, and medicinal chemistry - are also transforming psychiatry. The field stands poised to make dramatic advances in defining disease pathogenesis, developing diagnostic methods capable of identifying specific and valid disease entities, discovering novel and more effective treatments, and ultimately preventing psychiatric disorders. The Neurobiology of Mental Illness is written by world-renowned experts in basic neuroscience and the patho...
Emergent Brain Dynamics
Experts explore the maturation of nonlinear brain dynamics from a developmental perspective and consider the relationship of neurodevelopmental disorders to early disruption in dynamic coordination. This volume in the Strüngmann Forum Reports series explores the complex mechanisms that accompany the dynamic processes by which the brain evolves and matures. Integrating perspectives from multiple disciplines, the book identifies knowledge gaps and proposes innovative ways forward for this emerging area of cross-disciplinary study. The contributors examine maturation of nonlinear brain dynamics across systems from a developmental perspective and relate these organizing networks to the establis...
Neurolaw and Criminal Jurisprudence in India
This work explores the transformative potential of neuroscience in reshaping India's criminal justice system. It deftly navigates the complex terrain of neurolaw, examining its implications for criminal responsibility, rehabilitation, and the very foundations of legal thought. Drawing on cutting-edge neuroscientific research and India's rich philosophical traditions, the work proposes innovative approaches to longstanding legal and ethical dilemmas. It covers a wide range of topics with depth and nuance, from a neurocriminological audit of Indian criminal codes to an exploration of neuroplasticity in offender rehabilitation. It includes a fascinating case study of the Vipassana meditation pr...
Machine Learning, revised and updated edition
MIT presents a concise primer on machine learning—computer programs that learn from data and the basis of applications like voice recognition and driverless cars. No in-depth knowledge of math or programming required! Today, machine learning underlies a range of applications we use every day, from product recommendations to voice recognition—as well as some we don’t yet use every day, including driverless cars. It is the basis for a new approach to artificial intelligence that aims to program computers to use example data or past experience to solve a given problem. In this volume in the MIT Press Essential Knowledge series, Ethem Alpaydin offers a concise and accessible overview of ...
Innate
"What makes you the way you are--and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive the world. We all share a genetic program for making a human brain, and the program for making a brain like yours is specifi...
The Pragmatic Turn
Experts from a range of disciplines assess the foundations and implications of a novel action-oriented view of cognition. Cognitive science is experiencing a pragmatic turn away from the traditional representation-centered framework toward a view that focuses on understanding cognition as “enactive.” This enactive view holds that cognition does not produce models of the world but rather subserves action as it is grounded in sensorimotor skills. In this volume, experts from cognitive science, neuroscience, psychology, robotics, and philosophy of mind assess the foundations and implications of a novel action-oriented view of cognition. Their contributions and supporting experimental eviden...
Youth Mental Health
Experts discuss the potential of early intervention to transform outcomes for people with mental disorders. Mental illness represents one of the largest disease burdens worldwide, yet treatments have been largely ineffective in improving the quality of life for millions of affected individuals—in part because approaches taken have focused on late-stage disorders in adulthood. This volume shifts the focus by placing the developmental stage of “youth” at the center of mental health. The contributors challenge current nosology, explore mechanisms that underlie the emergence of mental disorders, and propose a framework to guide early intervention. Offering recommendations for the future, t...
Quick Fixes
This is your nation's history on drugs Americans are stumbling through a world-historic drug binge. Opiates, amphetamines, benzodiazepines, marijuana, antidepressants, antipsychotics-across the board, consumption has shot up in the twenty-first century. At the same time, the United States is home to the largest prison system in the world, justified in part by a now zombified "war" on drugs. How did we get here? Quick Fixes blows away the pharmacological fog to take a sober look at how drugs have shaped American society. Though particularly acute in recent decades, the contradiction between America's passionate love for and intense hatred of these sub - stances has been one of its defining ch...
