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Promoting Safety of Medicines for Children
Monitoring the safety of medicine use in children is of paramount importance since during the clinical development of medicines only limited data on this aspect are generated through clinical trials. Use of medicines outside the specifications described in the license (e.g. in terms of formulation indications contraindications or age) constitutes off-label and off-license use and these are a major area of concern. These guidelines are intended to improve awareness of medicine safety issues among everyone who has an interest in the safety of medicines in children and to provide guidance on effective systems for monitoring medicine safety in pediatric populations. This book will be of interest to all health care professionals medicine regulatory authorities pharmacovigilance centres academia the pharmaceutical industry and policy-makers. Systems for monitoring medicine safety are described in Annex 1. Pharmacovigilance methods and some examples of recent information on adverse reactions to marketed medicines are discussed in Annex 2.
Surgical Treatment of Colorectal Cancer
This book presents an Asian perspective on how the treatment of colorectal cancer can be optimized and standardized in ways that take into account technological advances and the trend towards individually tailored therapy. Readers will find careful, well-illustrated descriptions of the standard surgical techniques for rectal cancer and colon cancer that have contributed to recent improvements in 5-year survival rates in the Asia-Pacific region, where the incidence of colorectal cancer has been rising alarmingly due to lifestyle changes. The vital role now being played by minimally invasive laparoscopic and robotic options receives detailed scrutiny. Extent and timing of surgery, patient safety, risk of complications, and unresolved issues are all discussed. Furthermore, the use of surgery within the context of multimodal management including chemotherapy and radiotherapy is explained and an integrated approach for stage IV and recurrent disease is described. The book will serve as a valuable reference for young surgeons who are in training, experienced practitioners who want to enhance their knowledge and skills, and all others who wish to learn about this field.
Practical Pharmaceutics
This book contains essential knowledge on the preparation, control, logistics, dispensing and use of medicines. It features chapters written by experienced pharmacists working in hospitals and academia throughout Europe, complete with practical examples as well as information on current EU-legislation. From prescription to production, from usage instructions to procurement and the impact of medicines on the environment, the book provides step-by-step coverage that will help a wide range of readers. It offers product knowledge for all pharmacists working directly with patients and it will enable them to make the appropriate medicine available, to store medicines properly, to adapt medicines i...
Global Trends in Human Resource Management
Provides an understanding of how HRM policies and practices differ across countries and how the development of management practice may be affected by different institutional and cultural contexts. Containing contributions from a range of well-respected HRM scholars across the world, this collection is based upon data from a unique research project.
Medieval Jewelry and Burial Assemblages in Croatia
The Croatian medieval archaeological heritage from the 8th to the 15th century consists mostly of jewelry (earrings) findings from cemeteries. This book uses vertical and horizontal stratigraphy, on the basis of around 20,000 burial assemblages from 16 cemeteries (out of several hundred so far excavated in Croatia), to establish relative and absolute chronology of jewelry and burial architecture divided into three horizons and four phases in comparison with materials from neighboring regions of Europe.
The Evolving Threat of Antimicrobial Resistance
Antibiotic resistance development is a natural process of adaption leading to a limited lifespan of antibiotics. Unnecessary and inappropriate use of antibiotics favours the emergence and spread of resistant bacteria. A crisis has been building up over decades, so that today common and life-threatening infections are becoming difficult or even impossible to treat. It is time to take much stronger action worldwide to avert an ever increasing health and economic burden. A new WHO publication "The evolving threat of antimicrobial resistance--Options for action" describes examples of policy activities that have addressed AMR in different parts of the world. The aim is to raise awareness and to stimulate further coordinated efforts.
The Reconnection
Why are prominent doctors and medical researchers all over the world interested in the extraordinary healings reported by the patients of Dr. Eric Pearl? What does it mean when these patients report the sudden disappearance of afflictions such as cancers, AIDS-related diseases, and cerebral palsy? And what does it mean when people who interact with Dr. Pearl report a sudden ability to access this healing energy not just for themselves, but for others, too? What is this phenomenon? Well, you might have to reconsider everything you've read up until now about conventional healing. The ''new'' frequencies of healing described by Dr. Pearl transcend ''technique'' entirely and bring you to levels beyond those previously accessible to anyone, anywhere. This book takes you on Dr. Pearl's journey from the discovery of his ability to facilitate healings, to his well-deserved reputation as the instrument through which this process is being introduced to the world. But most important, The Reconnection reveals methods you can use to personally master these new healing energies.
Ultrasound-Assisted Liposuction
Liposuction is currently the number one aesthetic surgical procedure performed by plastic surgeons in the United States and Americans spend more money on liposuction than on any other aesthetic surgical procedure. Almost 500,000 cases are currently performed yearly by board certified plastic surgeons and it is estimated that at least 20% of the cases are ultrasound assisted. Current ultrasonic liposuction devices are significantly different than the previous generations and require a certain level of technical expertise in order to achieve good outcomes with the technique. Although there are chapters devoted to the technique in general body contouring textbooks, there are no current textbook...
