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Drug delivery is a term that refers to the delivery of a pharmaceutical compound to humans or animals. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Many medications, however, can not be delivered using these routes because they might be susceptible to degradation or are not incorporated efficiently. For this reason many protein and peptide drugs have to be delivered by injection. For example, many immunisations are based on the delivery of protein drugs and are often done by injection. Current efforts in the area of drug delivery include the development of targeted delivery in which the drug is only active in the target area of the body (for example, in cancerous tissues) and sustained release formulations in which the drug is released over a period of time in a controlled manner from a formulation. This new book focuses on worldwide research on drug delivery and targeting at the molecular, cellular, and higher levels.
For better or worse, the former Soviet republics of Central Asia have largely completed their post-independence transitions. Over more than a decade, they have established themselves as independent states whose internal regimes and external relations have characteristic patterns and vulnerabilities both individually and as a group. The purpose of this volume is to assess both what has been accomplished and the trends of development in the region, especially its leading states. How sound are the foundations of this "bulwark against the spread of terrorism" in Eurasia?
Kazakhstan is emerging as the most dynamic economic and political actor in Central Asia. It is the second largest country of the former Soviet Union, after the Russian Federation, and has rich natural resources, particularly oil, which is being exploited through massive US investment. Kazakhstan has an impressive record of economic growth under the leadership of President Nursultan Nazarbaev, and has ambitions to project itself as a modern, wealthy civic state, with a developed market economy. At the same time, Kazakhstan is one of the most ethnically diverse countries in the region, with very substantial non-Kazakh and non-Muslim minorities. Its political regime has used elements of politic...
____________________ THE EXPLOSIVE NEW YORK TIMES BESTSELLER 'A bombshell.' Daily Mail 'Damning, terrifying and enraging.' The Spectator ____________________ House of Trump, House of Putin offers the first comprehensive investigation into the decades-long relationship among Donald Trump, Vladimir Putin, and the Russian Mafia that ultimately helped win Trump the White House. As Unger traces Donald Trump's sordid ascent from foundering real estate tycoon to leader of the free world, House of Trump, House of Putin, reveals the deep-rooted alliance between the highest echelons of American political operatives and the biggest players in the frightening underworld of the Russian Mafia. Examining R...
Dmitrii Shepilov (1905-1995), a prominent Soviet leader and member of the Communist Party elite, rose to power under Joseph Stalin in the 1940s and 1950s, then fell into political disgrace after being implicated in a coup attempt against Nikita Khrushchev in 1957. In this remarkable memoir, Shepilov provides an unparalleled account of Soviet politics during this period, as well as first-hand recollections of prominent political leaders including Stalin, Khrushchev, Mao Zedong, Lavrentii Beria, Andrei Zhdanov, and others. Secretary of the Central Committee, editor in chief of Pravda, and director of the Communist Party’s Bureau of Propaganda and Agitation, Shepilov tells his story from the perspective of a true insider. His memoir sheds new light on Soviet relations with China, the aborted coup against Khrushchev, the personal rivalries that drove high-level Soviet politics, and much more. His report--dramatic, opinionated, and engaging--is an important addition to the history of his sparsely documented era.
One of the most exciting movements in 20th century art, Russian constructivism radically reassessed the role of the artist and his work. Here, Lodder provides a detailed account of this complex movement and the reverberations it had on Western culture.