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Southeast Asian Affairs 2022
“Southeast Asian Affairs, first published in 1974, continues today to be required reading for not only scholars but the general public interested in in-depth analysis of critical cultural, economic and political issues in Southeast Asia. In this annual review of the region, renowned academics provide comprehensive and stimulating commentary that furthers understanding of not only the region’s dynamism but also of its tensions and conflicts. It is a must read.” – Suchit Bunbongkarn, Emeritus Professor, Chulalongkorn University “Now in its forty-ninth edition, Southeast Asian Affairs offers an indispensable guide to this fascinating region. Lively, analytical, authoritative, and acce...
The China Problem in Postwar Japan
The 1970s were a period of dramatic change in relations between Japan and the People's Republic of China (PRC). The two countries established diplomatic relations for the first time, forged close economic ties and reached political agreements that still guide and constrain relations today. This book delivers a history of this foundational period in Sino-Japanese relations. It presents an up-to-date diplomatic history of the relationship but also goes beyond this to argue that Japan's relations with China must be understood in the context of a larger “China problem” that was inseparable from a domestic contest to define Japanese national identity. The China Problem in Postwar Japan challenges some common assertions or assumptions about the role of Japanese national identity in postwar Sino-Japanese relations, showing how the history of Japanese relations with China in the 1970s is shaped by the strength of Japanese national identity, not its weakness.
Antibiotic Discovery and Development
This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
Acute Side Effects of Radiation Therapy
This book provides clear guidance on how to manage a wide range of side effects frequently encountered when treating patients with radiation therapy. For each potential side effect, incidence, mechanism, symptoms, and grading are carefully described. All aspects of management are addressed, drawing on the latest available evidence and highlighting key details of importance in clinical routine. The introduction of new radiation therapy techniques such as 3D conformal radiation therapy, intensity-modulated radiation therapy, and image-guided radiation therapy has reduced normal tissue doses and, accordingly, treatment complications. Nevertheless, a significant percentage of patients still experience acute side effects, in part because the threshold doses for these toxicities are typically lower than those for late effects. Acute toxicities may lead to interruption of treatment and be associated with an increase in late damage. A swift and effective response is therefore essential. This book will enable the reader to provide effective care for each side effect, thereby improving patient compliance with treatment and treatment outcomes.
Asia-Pacific Regional Security Assessment 2021
The Asia-Pacific Regional Security Assessment 2021 provides insight into key regional strategic, geopolitical, economic, military and security topics. Among the topics explored are: US−China decoupling and its regional security implications; Japan’s security policy and China; India’s emerging grand strategy; Southeast Asia amid rising great-power rivalry; Australia’s new regional security posture; NATO’s evolving approach to China; The United Kingdom’s ‘tilt’ to the Indo-Pacific; and Emerging technologies and future conflict in the Asia-Pacific. Authors include leading regional analysts and academics Kanti Bajpai, Gordon Flake, Franz-Stefan Gady, Prashanth Parameswaran, Alessio Patalano, Samir Puri, Sarah Raine, Tan See Seng, Drew Thompson, Ashley Townshend, Joanne Wallis and Robert Ward.
The Mekong
A “remarkable” history of the great river of Southeast Asia (Jill Ker Conway, author of The Road from Coorain). The Mekong River runs over nearly three thousand miles, beginning in the mountains of Tibet and flowing through China, Burma, Laos, Thailand, Cambodia, and Vietnam before emptying into the China Sea. Its waters are the lifeblood of Southeast Asia, and first begot civilization on the fertile banks of its delta region at Oc Eo nearly two millennia ago. This is the story of the peoples and cultures of the great river, from these obscure beginnings to the emergence of today’s independent nations. Drawing on research gathered over forty years, Milton Osborne traces the Mekong’s ...
Biogenesis of Fatty Acids, Lipids and Membranes
Concise chapters, written by experts in the field, cover a wide spectrum of topics on lipid and membrane formation in microbes (Archaea, Bacteria, eukaryotic microbes).All cells are delimited by a lipid membrane, which provides a crucial boundary in any known form of life. Readers will discover significant chapters on microbial lipid-carrying biomolecules and lipid/membrane-associated structures and processes.
Membrane Biogenesis
Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achieveme...
