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Behavioral Neurobiology of Chronic Pain
Pain is the most common reason people seek medical help. The treatment of chronic pain is a major unmet clinical need and its impact on health, well-being, society and the economy is immense. Pain is an integrative, whole-systems (patho)physiological phenomenon and behavioural neuroscience plays a key role in advancing our understanding of pain. This volume brings together a series of authoritative chapters written by leading experts in preclinical and clinical aspects of pain neurobiology. Behavioural approaches to the study of persistent or chronic pain in animal models or humans are at the core of the volume, but the anatomical, physiological, neurochemical and molecular mechanisms that underpin behavioural alterations are also emphasized.
Handbook of Microdialysis
Microdialysis is currently one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to determine the concentrations and identities of molecules in brain tissues, and their change due to behavior, hormonal and transmitter changes in the nervous system. The book provides a detailed comprehensive overview of the technology and its applications, including application in pathology, drug development, and the application in the clinic. The authors are all well kn...
The NPY Family of Peptides in Immune Disorders, Inflammation, Angiogenesis, and Cancer
Recent research indicates that the immune system and inflammatory reactions are governed and regulated by powerful neuronal mediators derived from the central and peripheral nervous system. The NPY family of peptides is a diverse group of neuropeptides that acts via multiple receptors, Y1-Y5, which are widespread not only in neurons but also in a variety of non-neural and immune cells. These peptides have been known as important regulators of many essential systems, such as blood pressure and cardiac function, food consumption and energy homeostasis. However, in recent years, they have also become recognized for their role as potent modulators of cell growth and immune functions with broad implications in chronic inflammatory diseases, cancer and angiogenesis. In this book, experts in the field analyze recent evidence supporting the role of NPY family of peptides in regulation of the immune/inflammatory system with special reference to its medical and therapeutic implications.
Directory of Members
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Finding a Voice at Work?
How much 'say' should employees have in the running of business organizations, and what form should the 'voice' take? This is both the oldest and latest question in employment relations. Answers to these questions reflect our fundamental assumptions about the nature of the employment relationship, and inform our views on almost every aspect of Human Resource Management (HRM) and Employment Relations. Voice can also mean different things to different people. For some, employee voice is a synonym for trade union representation which aims to defend and promote the collective interests of workers. For others voice, is means of enhancing employee commitment and organisational performance. Others ...
Polk City Directory
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Identification of Learning Disabilities
Identification of Learning Disabilities: Research to Practice is the remarkable product of a learning disabilities summit conference convened by the Office of Special Education Programs (OSEP) in August 2001 and the activities following that summit. Both the conference and this book were seen as important preludes to congressional reauthorization of the historic Individuals With Disabilities Education Act (IDEA) scheduled for 2002 and subsequent decision making surrounding implementation. The OSEP conference brought together people with different perspectives on LD (parents, researchers, practitioners, and policymakers) and resulted in this book, which examines the research on nine key issue...
Physics Briefs
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