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This authoritative and comprehensive volume presents a perspective in the molecular and cellular diversity of membrane ion channels. Written in an accessible format, it depicts the structure and function of each of the known classes of ion channels. Each chapter provides amino acid sequences, including data base accession numbers; views of secondary, tertiary and quaternary channel structure; and evolutionary relationships among channels.
Hospital and Haven tells the story of an Episcopal missionary couple who lived their entire married life, from 1910 to 1938, among the Gwich'in peoples of northern Alaska, devoting themselves to the peoples' physical, social, and spiritual well-being. The era was marked by great social disruption within Alaska Native communities and high disease and death rates, owing to the influx of non-Natives in the region, inadequate sanitation and hygiene, minimal law enforcement, and insufficient government funding for Alaska Native health care. Hospital and Haven reveals the sometimes contentious yet promising relationship between missionaries, Alaska Natives, other migrants, and Progressive Era medi...
Models and modelling play a central role in the nature of science, in its conduct, in the accreditation and dissemination of its outcomes, as well as forming a bridge to technology. They therefore have an important place in both the formal and informal science education provision made for people of all ages. This book is a product of five years collaborative work by eighteen researchers from four countries. It addresses four key issues: the roles of models in science and their implications for science education; the place of models in curricula for major science subjects; the ways that models can be presented to, are learned about, and can be produced by, individuals; the implications of all these for research and for science teacher education. The work draws on insights from the history and philosophy of science, cognitive psychology, sociology, linguistics, and classroom research, to establish what may be done and what is done. The book will be of interest to researchers in science education and to those taking courses of advanced study throughout the world.
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Evolutionary Biology, of which this is the nineteenth volume, continues to offer its readers a wide range of original articles, reviews, and com mentaries on evolution, in the broadest sense of that term. The topics of the reviews range from anthropology and behavior to molecular biology and systematics. In recent volumes, a broad spectrum of articles have appeared on such subjects as natural selection among replicating molecules in vitro, mate recognition and the reproductive behavior in Drosophila, evolution of the monocotyledons, species selection, and the communication net work made possible among even distantly related genera of bacteria by plasmids and other transposable elements. Arti...
Cytochromes c are haemoproteins which carry out electron transfer in a wide variety of biological systems, necessitating different kinds of cytochrome c to fulfill different biological roles. The evolutionary relationship between cytochromes c and their host organisms are described, as well as their structural, spectroscopic and redox properties, including both electron-transfer rates and redox potentials. The treatment is aimed at the non-specialist so that both the techniques described and their application to cytochromes c can be understood. All classes of cytochrome c are dealt with to provide a comprehensive account of the field. No other text provides such a broad survey. Similar to the earlier volume "Cytochromes c: Biological Aspects" which deals with the classification, biosynthesis and biological role of cytochromes c, the present book is aimed at research workers and advanced students.
The book focuses on the archaeology of the Late Geometric and Early Archaic North-Eastern Aegean through the emergence, manufacture, distribution and consumption of a regional pottery group known as G 2-3 Ware. It offers the first comprehensive, in-depth study through combination of scientific (fabric analysis) and traditional (morphological, stylistic, comparative and distribution analysis) methods. The large body of studied material allows for drawing conclusions on a broader geographical and historical scale, in contrast to earlier studies focused on individual sites. The manufacture, distribution and consumption patterns are characterised by diversity, which reflects a dynamic, multiethn...