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Quality measurement, control, and improvement in combinatorial chemistry Combinatorial chemistry has developed rapidly in the past decade, with great advances made by scientists working on analysis and purification of a large number of compounds and the analysis of polymer-bound compounds. However, formidable challenges lie ahead of today's researcher. For example, high-throughput analysis and purification technologies must be further developed to ensure combinatorial libraries are "purifiable," and "drugable." To this end, Analysis and Purification Methods in Combinatorial Chemistry describes various analytical techniques and systems for the development, validation, quality control, purific...
The Hormones: Physiology, Chemistry and Applications, Volume V covers the advances in understanding the nature and function of hormones. This seven-chapter volume is a continuation of Volume IV on the endocrinology of plant and non-mammalian animal hormones. The introductory chapters examine the structure, metabolite actions, and some other chemical aspects of pituitary hormones. The following chapter explores the physiological, biochemical, and phylogenetic aspects of thyroid hormones, as well as brief description of thyroid cytology and process kinetics related to the thyroid. This chapter also presents mathematical models describing the processes of accumulation and binding of iodide in t...
"Provides comprehensive coverage of the current combinatorial methodologies and technologies employed for the design, synthesis, and screening of molecular ""libraries."" Features assessments of computer-assisted approaches to guiding library synthesis. Designed to satisfy the demand to create, produce in high yield and purity, and rapidly screen huge numbers of molecules."
"This is MacLean's major work on the evolutionary development of the human brain. In its evolution the human forebrain expands along the lines of three basic formations that anatomical and biochemically reflect an ancestral relationship, respectively, to reptiles, early mammals, and late mammals. MacLean describes this as the Triune Brain."--Amazon.com viewed July 29, 2020