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For dog owners and lovers everywhere, C. J. Frick's Be the Person Your Dog Thinks You Are is a humorous, fully illustrated book that shows us that even when we feel at our worst, our dogs still think we’re the best—so start acting like it!
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English abstracts from Kholodil'naia tekhnika.
UW Archives holds up to three copies of each volume of the yearbook from its initial publication in 1884 to its final publication in 2014 (129 volumes). The publication of the yearbook did not become annual until 1887, as such there are no yearbooks for 1885 or 1886. The only other interruption in yearbooks was for the years 1973 and 1974. There are still yearbooks from these years, but they were published by the Wisconsin Alumni Association rather than the student body, as such they are spare, consisting mostly of portraits of students. UW Archives currently holds at least one copy of every published volume. The 1st copy of each volume is held onsite at UW Archives while the second and third copies, where they exist, are held offsite.
Soil is the most important natural non-renewable resource developed over a longer period of time due to weathering of rocks and subsequently enrichment of organic matter. Soil provides habitat for numerous microorganisms and serves as a natural medium for plant growth, thereby providing the plants with anchorage, nutrients and water to sustain the growth. Soil also serves as a universal sink for all types of pollutants, purifies ground water and is a major reserve of carbon in the universe. The role of soils to provide ecosystem services, maintenance of environmental/human health and ensuring the food security makes it as the most important and basic natural resource. Soil Science helps us t...
Lung cancer is one of the leading causes of cancer-related death worldwide with a prevalence of advanced stage in up to 70% of cases and a five-year survival reached in only 5-10% of cases. Targeted therapies and immunotherapy have greatly improved the management of patients with advanced non-small cell lung cancer (NSCLC), particularly adenocarcinoma, and current diagnostic algorithms are based on the molecular analysis of several biomarkers necessary to tailor therapy. In detail, patients harboring sensitive driver alterations within the oncogenes EGFR, BRAF, ALK, ROS1, RET and NTRK1/2/3 can be treated with approved kinase inhibitors (KIs). In addition, drugs against MET, KRAS G12C and other markers are providing interesting results across different clinical trials. Targeted therapies have greatly improved therapeutic options for NSCLC, but resistance inevitably occurs usually after one year of treatment and some patients, although harboring sensitive alterations, never respond to treatment.