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The rising costs of medicines is a major burden for healthcare systems and is already limiting access to innovative treatments worldwide. Governments, healthcare providers and payers constantly try to improve the sustainability of drug development, production, pricing and use of medicines. The aim of this research topic is to identify strategies and policies that can facilitate sustainable development and use of medicines as well as practical solutions to improve their cost-effectiveness. For this topic, we are also interested in alternative pricing strategies and financial arrangements, requisite changes in regulatory and legal frameworks to support sustainability, the potential role of reg...
The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis. Edited by prominent scientists working in drug discovery for Pfizer Meets the needs of a growing community of researchers in pharmaceutical R&D Provides a useful guide for practicing pharmaceutical scientists as well as a text for medicinal chemistry students An excellent follow-up to the very successful first book by these editors, Contemporary Drug Synthesis, but with all new therapeutic categories and drugs discussed.
This second and expanded edition of the first book on agromining (phytomining) presents a comprehensive overview of the metal farming & recovery of the agromining production chain. Agromining is an emerging technology that aims to transform the extraction of sources of target elements not accessible by traditional mining and processing techniques. Agromining, which is based on sustainable development, uses hyperaccumulator plants as 'metal crops' farmed on sub-economic soils or minerals wastes to obtain valuable target elements. This volume is edited and authored by the pioneers in the rapidly expanding field of agromining and presents the latest insights and developments in the field. This ...
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pt. 1. List of patentees.--pt. 2. Index to subjects of inventions.