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Connections, Cognition and Alzheimer’s Disease
The fundamental relationship between the neuropathological lesions of Alzheimer's disease and the problem of what underlies the clinical syndrome has remained unsolved since the beginning of the century. Are neurofibrillary tangles and senile plaques directly related to clinical symptoms, or are they epiphenomena that signal synaptic and neuronal loss? In the last decade, these questions have been revisited through systematic studies of individuals with various degrees of dementia using newer immunohistochemical techniques and quantitative approaches to neuropathological study. It is now possible to have a uniform picture of Alzheimer's disease dementia as resulting from collapse of specific neural systems, as pathological changes selectively and specifically involve structures related to memory and higher cognitive functions.This book contains the proceedings of a meeting organized by the Fondation Ipsen which brought together researchers in neuropathology, molecular biology, genetics, neuropsychology, brain imagery and clinical neurology. .
The 9 Pillars of Resilience
Stress is a fact of life—and it’s necessary for success. Discover a holistic methodology based on 9 key pillars to help you thrive even in the midst of overwhelming stress. Individuals at all levels of society and income are feeling the exhausting effects of economic uncertainty, political upheaval, international conflict, the pandemic, and environmental devastation. This timely book offers effective approaches for overcoming everyday challenges, presenting you with the tools you need to neutralize stress, build resilience, and live a balanced life. Drawing on over 40 years of experience, Dr. Stephen I. Sideroff equips you with the techniques needed to adjust the mind and body to the evo...
Biomedical Advances in Aging
The VIIIth Annual International Spring Symposium on Health Sciences held at the George Washington University School of Medicine in Washington, D.C., attracted over three hun dred fifty scientists from twenty-five countries. The leading scientific experts in the field reported on recent biomedical advances in aging. They provided an up-to-date account of the molecular, genetic, nutritional, and immunological mechanisms associated with the aging process and approaches to intervention and treatment of the major disorders associated with the aging process, including Alzheimer's disease. A unique aspect of this meeting was a concurrent one-day hearing of the U.S. Senate Sub-Committee on Aging, organized by the Alliance for Aging Research. The theme for the hearing was "Advances in Aging Research." Seven scientists attending our aging sym posium were asked to testify. They were Drs. Carl Cotman (University of California-Irvine), Trudy Bush (Johns Hopkins University), Takashi Makinodan (University of California-Los Angeles), William Ershler (University of Wisconsin-Madison), Gino Doria (ENEA, Rome), Mr. Dan Perry (Director of the Alliance for Aging Research), and myself.
History of Exercise Physiology
Well illustrated with figures and photos, this text brings together leading authorities in exercise physiology to help readers understand the research findings and meet the most prominent professionals in the field.
Amyloid Protein Precursor in Development, Aging and Alzheimer’s Disease
This book summarizes the last ten years' research on Alzheimer's disease. Genetic mutations in the gene which codes for amyloid precursor protein (APP) have now been shown to cause Alzheimer's disease in some families. Other genetic loci are now being discovered which relate to Alzheimer's disease in some families. Understanding the normal structure and function of the APP gene product will eventually provide avenues for developing specific therapeutic strategies targeted at the amyloid deposition in the Alzheimer's disease brain. Drugs which can inhibit or dissolve the amyloid, affect the synthesis and proteolysis of APP, or which regulate the activity of the APP gene all hold the promise of eventually yielding an effective treatment for Alzheimer's disease.
Neurosciences at the Postgenomic Era
In this new volume in the series Research and Perspectives in Neurosciences the authors have presented and discussed their findings in the fields of speech and language disorders, X-linked mental retardation, gene therapy in the CNS, memory and learning disorders and other fields.
Exercise Is Medicine
Aging, despite its dismal reputation, is actually one of the great mysteries of the universe. Why don't we just reproduce, then exit fast, like salmon? Could aging just be one big evolutionary accident? Is senescence, the gradual falling apart of our bodies, at least partially avoidable? Can we extend the healthy lifespan and reduce the lingering, debilitating effects of senescence? In this book, investigative health journalist Judy Foreman suggests that we actually can, and the key element is exercise, through its myriad effects on dozens of molecules in the brain, the muscles, and other organs. It's no secret, of course, that exercise is good for you and that exercise can extend longevity....
Summary of John J. Ratey’s Spark by Milkyway Media
Spark: The Revolutionary New Science of Exercise and the Brain (2008), by John J. Ratey with Eric Hagerman, examines the often overlooked benefits that aerobic exercise has for the human brain. Exercise is as good for the mind as it is for the body, a point illustrated by the story of a school district in Naperville, Illinois... Purchase this in-depth summary to learn more.
