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Describes important modelling and computational methods for systems biology research to enable practitioners to select and use the most suitable technique Systems Biology Modelling and Analysis provides an overview of state-of-the-art techniques and introduces related tools and practices to formalize models and automate reasoning for systems biology. The authors present and compare the main formal methods used in systems biology for modelling biological networks, including discussion of their advantages, drawbacks, and main applications. Each chapter includes an intuitive presentation of the specific formalism, a brief history of the formalism and of its applications in systems biology, a fo...
This volume contains the proceedings of the 10th International Conference on Tools and Algorithms for the Construction and Analysis of Systems (TACAS 2004). TACAS 2004 took place in Barcelona, Spain, from March 29th to April 2nd, as part of the 7th European Joint Conferences on Theory and Practice of Software (ETAPS 2004), whose aims, organization, and history are detailed in a foreword by the ETAPS Steering Committee Chair, Jos ́ e Luiz Fiadeiro. TACAS is a forum for researchers, developers, and users interested in ri- rously based tools for the construction and analysis of systems. The conference serves to bridge the gaps between di?erent communities including, but not - mited to, those d...
Includes tutorials, lectures, and refereed papers on all aspects of logic programming, including theoretical foundations, constraints, concurrency and parallelism, deductive databases, language design and implementation, nonmonotonic reasoning, and logic programming and the Internet. The International Conference on Logic Programming, sponsored by the Association for Logic Programming, includes tutorials, lectures, and refereed papers on all aspects of logic programming, including theoretical foundations, constraints, concurrency and parallelism, deductive databases, language design and implementation, nonmonotonic reasoning, and logic programming and the Internet.
This book constitutes the refereed proceedings of the 5th International Conference on Verification, Model Checking, and Abstract Interpretation, VMCAI 2004, held in Venice, Italy in January 2004. The 22 revised full papers presented together with 4 invited contributions were carefully reviewed and selected from 68 submissions. The papers are organized in topical sections on security, formal methods, model checking, software checking, liveness and completeness, and miscellaneous.
This volume contains the proceedings of AMAST 2002, the 9th International Conference on Algebraic Methodology and Software Technology, held during September 9–13, 2002, in Saint-Gilles-les-Bains, R ́eunion Island, France. The major goal of the AMAST conferences is to promote research that may lead to setting software technology on a ?rm mathematical basis. This goal is achieved through a large international cooperation with contributions from both academia and industry. Developing a software technology on a mathematical basis p- duces software that is: (a) correct, and the correctness can be proved mathem- ically, (b) safe, so that it can be used in the implementation of critical systems,...
This postproceedings volume of the 17th International Symposium on Logic-Based Program Synthesis and Transformation, LOPSTR 2007, examines program termination, program transformation, constraint solving and analysis as well as software engineering.
This volume contains the proceedings of FMOODS 2003, the 6th IFIP WG 6. 1 International Conference on Formal Methods for Open Object-Based Distributed Systems. The conference was held in Paris, France on November 19–21, 2003. The event was the sixth meeting of this conference series, which is held roughly every year and a half, the earlier events having been held in Paris, Canterbury, Florence, Stanford, and Twente. ThegoaloftheFMOODSseriesofconferencesistobringtogetherresearchers whose work encompasses three important and related ?elds: – formal methods; – distributed systems; – object-based technology. Such a convergence is representative of recent advances in the ?eld of distribut...
ETAPS 2001 was the fourth instance of the European Joint Conferences on Theory and Practice of Software. ETAPS is an annual federated conference that was established in 1998 by combining a number of existing and new conferences. This year it comprised ve conferences (FOSSACS, FASE, ESOP, CC, TACAS), ten satellite workshops (CMCS, ETI Day, JOSES, LDTA, MMAABS, PFM, RelMiS, UNIGRA, WADT, WTUML), seven invited lectures, a debate, and ten tutorials. The events that comprise ETAPS address various aspects of the system de- lopment process, including speci cation, design, implementation, analysis, and improvement. The languages, methodologies, and tools which support these - tivities are all well within its scope. Di erent blends of theory and practice are represented, with an inclination towards theory with a practical motivation on one hand and soundly-based practice on the other. Many of the issues involved in software design apply to systems in general, including hardware systems, and the emphasis on software is not intended to be exclusive.
Cyber-physical systems (CPSs) combine cyber capabilities, such as computation or communication, with physical capabilities, such as motion or other physical processes. Cars, aircraft, and robots are prime examples, because they move physically in space in a way that is determined by discrete computerized control algorithms. Designing these algorithms is challenging due to their tight coupling with physical behavior, while it is vital that these algorithms be correct because we rely on them for safety-critical tasks. This textbook teaches undergraduate students the core principles behind CPSs. It shows them how to develop models and controls; identify safety specifications and critical properties; reason rigorously about CPS models; leverage multi-dynamical systems compositionality to tame CPS complexity; identify required control constraints; verify CPS models of appropriate scale in logic; and develop an intuition for operational effects. The book is supported with homework exercises, lecture videos, and slides.
The multiset, as a set with multiplicities associated with its elements in the form of natural numbers, is a notation which has appeared again and again in various areas of mathematics and computer science. As a data structure, multisets stand in-between strings/lists, where a linear ordering of symbols/items is present, and sets, where no ordering and no multiplicity is considered. This book presents a selection of thoroughly reviewed revised full papers contributed to a workshop on multisets held in Curtea de Arges, Romania in August 2000 together with especially commissioned papers. All in all, the book assesses the state of the art of the notion of multisets, the mathematical background, and the computer science and molecular computing relevance.