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An Information Technology Framework for Predictive, Preventive and Personalised Medicine
This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.
Contrast Media
This is the third edition of a very successful book that originally emerged from the work of a committee set up by the European Society of Urogenital Radiology in 1994 to consider the safety of contrast media used for diagnostic imaging. The new edition not only fully updates the previous edition, but also includes new chapters on complex topics such as pediatric issues and practical aspects of off-label contrast media use. Comprehensive consideration is given to the many different safety issues relating to iodine-based contrast media, gadolinium-based contrast media, microbubbles for ultrasound, and barium sulfate. The text includes chapters on both acute and delayed non-renal adverse reactions and on renal adverse reactions. All of the questions frequently raised in radiological practice are addressed. This book, presented in a handy, easy-to-use format, provides an invaluable, unique, and unparalleled source of information.
Emergency Radiology of the Chest and Cardiovascular System
This book provides an up-to-date, systematic review of all facets of emergency radiology in patients with chest trauma or pain with the aim of equipping the reader with a detailed knowledge of the various radiological patterns, which is essential in order to make a prompt diagnosis under circumstances when time is of critical importance. To this end, the indications, value, and results of the various emergency imaging modalities, including sonography and interventional radiology, are described and illustrated in the full range of blunt chest injuries and nontraumatic chest emergencies. Technological aspects, protocols tailored to the mechanism of injury, and post-processing techniques are also extensively covered. Emergency Radiology of the Chest and Cardiovascular System will be of value to general and interventional radiologists, radiology residents, radiology technicians, and all physicians and surgeons who work in emergency care.
Emergency Radiology of the Abdomen
The term “acute abdomen” refers to a serious, often progressive clinical situation that calls for immediate diagnostic and therapeutic action. Today, diagnosis via imaging has basically replaced the physical examination in the emergency room and the Radiologist has become of primary importance in this setting. However, close co-operation among the various specialists involved is essential for successful patient management, and thus the Radiologist needs to have a full understanding of the imaging modalities and technical skills required, as well as appropriate clinical knowledge of the disorder in order to manage the condition. This book provides a comprehensive review of the multifaceted etiology, pathophysiology and clinical presentation of acute abdominal conditions, focusing on the imaging features that are relevant to a timely management approach. Numerous high-quality images, diagrams and easy-to-read tables are provided.
Clinical MRI of the Abdomen
This volume, which explains why, when, and how abdominal MRI should be used, focuses in particular on the most recent developments in the field. After introductory chapters on technical considerations, protocol optimization, and contrast agents, MRI of the various solid and hollow viscera of the abdomen is addressed in a series of detailed chapters. Relevant clinical information is provided, and state of the art protocols presented. With the help of numerous high-quality illustrations, normal, variant, and abnormal imaging findings are described and potential artefacts highlighted. Differential diagnosis is given extensive consideration, and comparisons are made with competing methodologies when relevant. Each of the chapters is rounded off by a section on "pearls and pitfalls". The closing chapters focus on findings in the pediatric abdomen, advances in MRI specifically relevant to cancer patients, and the use of abdominal MRI at 3 Tesla. This book, written by leading experts, will be of value to all who are involved in learning, performing, interpreting, and reporting abdominal MRI examinations.
Imaging of the Larynx
Notwithstanding the important role of direct clinical and endoscopic examination in modern management of pathological conditions of the larynx, radiological study the and, more specifically, cross-sectional imaging by CT and MRI make definite diagnostic contributions by virtue of their potential to display superbly the deeper extent of laryngeal lesions. Indeed, remarkable progress has been achieved during recent years in CT and MRI techniques as applied to the neck region. This book sets out to provide a sorely needed update of our knowledge of the diagnostic potential of these cross-sectional methods and constitutes a very welcome addition to our series "Medical Radiology", which aims to c...
Dual Energy CT in Clinical Practice
Dual-energy CT is a novel, rapidly emerging imaging technique which offers important new functional and specific information. In this book, physicists and specialists from different CT manufacturers provide an insight into the technological basis of, and the different approaches to, dual-energy CT. Renowned medical scientists in the field explain the pathophysiological and molecular background of the technique, discuss its applications, provide detailed advice on how to obtain optimal results, and offer hints regarding clinical interpretation. The main focus is on the use of dual-energy CT in daily clinical practice, and individual sections are devoted to imaging of the vascular system, the thorax, the abdomen, and the extremities. Evaluations and recommendations are based on personal experience and peer-reviewed literature. Plenty of carefully chosen high-quality images are included to illustrate the clinical benefits of the technique.
New Concepts in Diagnosis and Therapy of Pancreatic Adenocarcinoma
This book adopts a multidisciplinary approach to examine in detail a range of interesting new concepts in the diagnosis and therapy of pancreatic adenocarcinoma. It is divided into three parts. The first part provides an epidemiological and clinical overview of the disease, followed by an update on pathological findings, including new discoveries in the area of molecular biology. The second part, on diagnosis, offers detailed and comprehensive information on the advantages and disadvantages of different imaging techniques, including nuclear medicine and endoscopic ultrasound. The concluding part gives a panoramic overview of the various therapeutic options, from surgery to chemotherapy and palliative approaches based on interventional endoscopy and radiology. This book will be a valuable source of information for clinicians involved in the management of pancreatic adenocarcinoma and for all who are interested in updating their knowledge of the disease, including fellows and senior residents.
Imaging of Complications and Toxicity following Tumor Therapy
Depending on their mechanism of action, the cytotoxic and targeted drugs and radiotherapy employed in oncologic treatment may cause complications and toxicities in many organ systems, with variable radiologic presentations. This comprehensive and excellently illustrated book covers the basics of therapy-induced complications and toxicities in oncologic patients, identifies their consequences for all the major organs, and describes the imaging of these impacts by means of the various radiologic modalities. By familiarizing radiologists with the most frequent and prominent toxicities that are recognizable on radiologic imaging following tumor therapy, it will facilitate identification of their early manifestations and permit differential diagnosis based on relevant findings.
Fetal MRI
This is the most comprehensive book to be written on the subject of fetal MRI. It provides a practical hands-on approach to the use of state-of-the-art MRI techniques and the optimization of sequences. Fetal pathological conditions and methods of prenatal MRI diagnosis are discussed by organ system, and the available literature is reviewed. Interpretation of findings and potential artifacts are thoroughly considered with the aid of numerous high-quality illustrations. In addition, the implications of fetal MRI are explored from the medico-legal and ethical points of view. This book will serve as a detailed resource for radiologists, obstetricians, neonatologists, geneticists, and any practitioner wanting to gain an in-depth understanding of fetal MRI technology and applications. In addition, it will provide a reference source for technologists, researchers, students, and those who are implementing a fetal MRI service in their own facility.
