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Sepsis is an important public health problem around the world. Severe sepsis carries significant morbidity, mortality and high costs. The incidence of sepsis is increasing because of the aging population, the growing number of immunocompromised hosts, the increasing use of invasive procedures, and, to a lesser extent, antibiotic resistance among pathogens. Despite recent advances in the pathogenesis, diagnosis, and therapeutic approaches the mortality rate associated with this condition remains high. Therefore, the goal of Sepsis: New Strategies is to review novel targets to be considered in patients with severe sepsis and to assess new developments for patients with sepsis originating in the respiratory tract.
Textbook of Critical Care, by Drs. Jean-Louis Vincent, Edward Abraham, Frederick A. Moore, Patrick Kochanek, and Mitchell P. Fink, remains your best source on effective management of critically ill patients. This trusted reference - acclaimed for its success in bridging the gap between medical and surgical critical care - now features an even stronger focus on patient outcomes, equipping you with the proven, evidence-based guidance you need to successfully overcome a full range of practice challenges. Inside, you’ll find totally updated coverage of vital topics, such as coagulation and apoptosis in certain critical care illnesses, such as acute lung injury and adult respiratory distress sy...
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This second edition provides detailed techniques used for the study and characterization of the plant vascular system, with a central focus on the xylem tissue. Chapters are organized in three main sections covering; analysis of xylem development, xylem characterization though imaging techniques, and analysis of the xylem composition. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Xylem: Methods and Protocols, Second Edition aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
The aim of the volume is to provide an authoritative and international treatise bringing together current knowledge in the field of respiratory infection. The book will be organised by presentation rather than causative organism, a differentiating feature from the existing competition, and will be divided into four parts - 'General Issues', 'Commun
This book reflects a major medical problem which is still under thorough studies. There is a number of clinical cases corresponding directly or indirectly to a certain alteration of the immune system, thus leading to various pathologic conditions. The unique defense, what humans have with their immunity, is rather often affected by infections, tumor processes, organ, tissue and cell transplantation, allergy, autoimmune processes, as well as different influences by the environment. The Book has an international team of authors all contributing to the investigation of the questions of what, why, how, when and where the immune system deviates from its normal function, what clinical consequences are manifested and is there a way to prevent and treat the immunodeficiency cases. This Book can be a very good teaching tool for students and post-docs of medicine and biology, but it also provides updated information for the colleagues immunologists, microbiologists, virologists, chemotherapists, oncologists, hematologists, transplantologists and pathologist.
The number of patients treated for hematological malignancies is increasing steadily. To maximize cure rates, aggressive treatments have been introduced, including high-dose chemotherapy, stem cell transplantation, and targeted therapies. As a result, overall and disease-free survival rates have improved substantially, but at the price of life-threatening toxic and infectious complications that chiefly target the lung. This book provides clinicians caring for patients with hematological malignancies with detailed, up-to-date information on all relevant aspects of pulmonary involvement. Individual sections are devoted to epidemiology, diagnostic strategy, lung infections, non-infectious pulmonary involvement, and treatment, including decision making in patients with acute respiratory failure. Each of these sections contains a number of chapters, all written by leading international experts. In addition, the reader’s attention is drawn to important "pearls" relating to each condition.
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The rise of Juan Perón to power in Argentina in the 1940s is one of the most studied subjects in Argentine history. But no book before this has examined the role the Peronists’ struggle with the major commercial newspaper media played in the movement’s evolution, or what the resulting transformation of this industry meant for the normative and practical redefinition of the relationships among state, press, and public. In The Fourth Enemy, James Cane traces the violent confrontations, backroom deals, and legal actions that allowed Juan Domingo Perón to convert Latin America’s most vibrant commercial newspaper industry into the region’s largest state-dominated media empire. An interdisciplinary study drawing from labor history, communication studies, and the history of ideas, this book shows how decades-old conflicts within the newspaper industry helped shape not just the social crises from which Peronism emerged, but the very nature of the Peronist experiment as well.