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The purpose of this book is to bring together the latest findings on metabolic disorders that are strongly implicated in various critically ill patients. Since the beginning of the 20th century, maintaining the "milieu intérieur" has been a major challenge for intensivists. In addition to considerable technological developments in intensive care units, important advances in our understanding of metabolic disorders observed in critically ill patients have been made during the 10 last years. Today, the intensivit can’t ignore these disorders when selecting the most appropriate treatment for an illness. Cellular metabolic abnormalities are responsible for systems and organ failures, so the m...
This book offers a pragmatic approach to day-to-day metabolic and nutritional care based on physiological considerations. Due to the numerous controversial trials published in the last 15 years, there is no clear guidance for intensive care physicians regarding the metabolic and nutritional management of patients. This has resulted in a return to underfeeding and related complications in most ICUs worldwide as shown by the latest Nutrition Day data. Using a structured, logical approach, the book examines practical solutions for artificial feeding in complex areas of critical care (brain injuries, burns, cardiac failure, ECMO, intestinal failure, long term patient, renal failure, metabolic diseases, obesity, old patients) and discusses measurement of the results of metabolic interventions. It also includes dedicated chapters focusing on specific problems, in order to avoid complications. Critical Care Nutrition Therapy for Non-nutritionists is a valuable resource for all general ICUs and ICU subspecialties such as cardiovascular, neuro, gastrointestinal and burns ICUs.
Hemofiltration is now recognised as the optimal therapeutic solution for supplying renal function in patients with acute renal failure associated with poor hemodynamic conditions This situation is often observed in patients with severe impairment in the function of one or several other organs Since its introduction in the intensive care units in the 1970s, hemofiltration has been subject to some major improvements regarding the required material and devices such as catheters, lines, filters, or pumps This progress has been accompanied by a better knowledge of the management of patients undergoing the technique, especially concerning nutritional support, drug administration, control of body temperature, as well as fluid and electrolytes balance or cost control Moreover, some additional beneficial effects of hemofiltration have been recently pointed out, suggesting that this technique could provide more than an already efficient renal support by removing some substances responsible for an exagger
For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.
This book highlights the practical characteristics of uncommon diseases and presents the most relevant features for the management of intensive care units. It does not aim to provide an exhaustive description of uncommon diseases, focusing instead on the major diseases that intensivists may encounter in their clinical practice. After a brief introduction on the epidemiology and pathophysiology of each disease, the authors emphasize the aspects related to diagnosis and treatment, providing concise and pragmatic guidance for residents and intensivists who care for patients with uncommon diseases. Although by definition uncommon diseases have a low prevalence in the general population, they can affect a large number of patients admitted to intensive care units, as they can often be diagnosed at intensive care units. Indeed, often a complication of the disease is what leads to the patient’s being admitted to an intensive care unit.
Les trois premières éditions de ce Traité portaient sur l’anesthésie et la réanimation chirurgicale. Cette 4e édition fait une synthèse plus large des connaissances scientifiques actuelles dans les domaines de l’anesthésie, de la réanimation et de la médecine péri-opératoire. Elle a pour originalité d’englober toutes les pathologies liées à l’anesthésie et la réanimation, en tenant compte de la diversité des équipes amenées à travailler dans ces domaines. Le Traité d’Anesthésie et de Réanimation, à la fois précis et exhaustif, aborde en 4 grandes parties et 109 chapitres les notions suivantes : – les questions générales de physiologie et de pharmacolog...
Almost nine months since the first recorded case, the novel betacoronovirus; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now passed 18 million confirmed cases. The multi-disciplinary work of researchers worldwide has provided a far deeper understanding of COVID-19 pathogenesis, clinical treatment and outcomes, lethality, disease-spread dynamics, period of infectivity, containment interventions, as well as providing a wealth of relevant epidemiological data. With 27 vaccines currently undergoing human trials, and countries worldwide continuing to battle case numbers, or prepare for resurgences, the need for efficient, high-quality pipelines for peer-reviewed research remains as crucial as ever.
This book demonstrates how the latest insights into the physiopathology of the stress response can be integrated into clinical practice. The topic is particularly relevant since the metabolic changes triggered by acute stress, including adaptive responses such as resistance to anabolic signals, have recently been more precisely delineated. The underlying mechanisms of these changes are also now better understood. The authors analyse how these advances could result in better management and more effective prevention of the long-term clinical consequences of the alterations occurring during the acute phase. An international panel of respected experts discusses these topics and describes the management of some common clinical conditions.
Cet ouvrage se fixe pour objectif de rendre accessible aux lecteurs les données actuelles de la littérature expérimentale et clinique. Il focalise l’attention sur les situations cliniques caractérisées par le retentissement rénal des principales dysfonctions des fonctions vitales dont le pronostic est aggravé par la survenue de cette insuffisance rénale. Enfin, les données physiopathologiques issues des modèles expérimentaux trouvent progressivement leur écho dans le domaine de la clinique ouvrant des pistes thérapeutiques dont les évaluations récentes seront analysées.