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The Biochemistry of Retinoid Signaling III
This book covers subjects that have major impacts on society, such as the mechanism of maternal-fetal transfer of vitamin A, and the effects of alcohol on retinoic acid signaling and mammalian embryonic development. There has been an awareness of the importance of consuming vitamins throughout human history, but empirical studies of their physiological role and mode of action only began about 150 years ago. Since then, the biochemical nature of vitamin A and its active derivative, retinoic acid, have been identified and researchers around the globe have investigated retinoic acid’s physiological function in growth processes and in maintaining life Written by leading experts, this book discusses the latest findings and advances in retinoic acid research. It addresses topics such as the role of retinoic acid signaling in a multitude of processes, including limb, heart and respiratory system development, as well as its role in maintaining postnatal organ systems. This book is a valuable resource for scientists involved in vitamin A/retinoic acid research and readers interested in developmental biology.
The Biochemistry of Retinoid Signaling II
The role of vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes, and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate models to study a multiplicity of processes and conditions, encompassing embryogenesis, postnatal development to old age. A wealth of intercellular interactions, intracellular signaling systems, and molecular mechanisms have been described and the overall conclusion is that retinoic acid is essential for...
Cell Signaling, Transcription, and Translation as Therapeutic Targets
The papers in this volume focus on developments in the area of signal transduction and gene expression related to diseases and their therapy. Research papers explore leading therapeutic approaches including novel antibodies against receptors, protein kinase inhibitors and gene expression.
Signal Transduction Pathways, Chromatin Structure, and Gene Expression Mechanisms as Therapeutic Targets
This volume describes recent findings in the field of fundamental signal transduction mechanisms, including protein kinesis as therapeutic targets as well as applied research toward angiogenesis, apoptosis, and chemopreventive agents.
Nature
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