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Neurobiology of Depression
Major depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry, mol
Focus on Serotonin Uptake Inhibitor Research
The most significant class of antidepressants marketed in recent years is the selective serotonin re-uptake inhibitors (SSRIs). Claims of decreased adverse effects (ADRs) and increased safety have led to extensive use of these drugs by non-psychiatrists. The six SSRIs available in the United States are citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft). The primary uses for the SSRIs include unipolar and bipolar major depression and all of the anxiety disorders. However, controlled trials also support the use of SSRIs in the treatment of other psychiatric disorders including dysthymia, pre-menstrual dysphoria, bulimia nervosa, obesity, borderline personality disorder, alcoholism, rheumatic pain, and migraine headache. This new book presents leading-edge research from throughout the world on this topic.
From Photography to fMRI
Hysteria, a mysterious disease known since antiquity, is said to have ceased to exist. Challenging this commonly held view, this is the first cross-disciplinary study to examine the current functional neuroimaging research into hysteria and compare it to the nineteenth-century image-based research into the same disorder. Paula Muhr's central argument is that, both in the nineteenth-century and the current neurobiological research on hysteria, images have enabled researchers to generate new medical insights. Through detailed case studies, Muhr traces how different images, from photography to functional brain scans, have reshaped the historically situated medical understanding of this disorder that defies the mind-body dualism.
The General History of Drugs Volume Three Part One
Drug history from the Renaissance through the nineteenth century.
Transhumanism, Ethics and the Therapeutic Revolution
This book explores the impact of developments in pharmaceutical medicine in the twentieth century on a Christian ethical evaluation of transhumanism and future "hi-tech" medical enhancement technologies. It suggests that the Christian ethical assessment of proposed future radical transhumanist biomedical technologies should be conducted in the light of responses to past medical advances. Two specific case studies are featured, focusing on the oral contraceptive pill and on Prozac and selective serotonin reuptake inhibitor (SSRI) antidepressants. Whilst future biomedical technologies may have therapeutic benefits for the relief of disease and contribute to improving human health and welfare, the book considers the implications for society and their acceptability as therapies from a Christian perspective. Stressing the inadequacy of natural law alone, the author proposes an ethical framework for assessing novel biomedical technologies according to the effects on personal autonomy, embodiment and bodily life, and on the imago Dei.
Practicing Biomedicine at the Albert Schweitzer Hospital 1913-1965
Tizian Zumthurm uses the extraordinary hospital of an extraordinary man to produce novel insights into the ordinary practice of biomedicine in colonial Central Africa. His investigation of therapeutic routines in surgery, maternity care, psychiatry, and the treatment of dysentery and leprosy reveals the incoherent nature of biomedicine and not just in Africa. Reading rich archival sources against and along the grain, the author combines concepts that appeal to those interested in the history of medicine and colonialism. Through the microcosm of the hospital, Zumthurm brings to light the social worlds of Gabonese patients as well as European staff. By refusing to easily categorize colonial medical encounters, the book challenges our understanding of biomedicine as solely domineering or interactive.
Personal Genome Medicine
In the years following FDA approval of direct-to-consumer, genetic-health-risk testing, millions of people in the United States have sent their DNA to companies to receive personal genetic health risk information without physician or other learned medical professional involvement. In Personal Genome Medicine, Michael J. Malinowski examines the ethical, legal, and social implications of this development. Drawing from the past and present of medicine in the U.S., Malinowski applies law, policy, public and private sector practices, and governing norms to analyze the commercial personal genome sequencing and testing sectors and to assess their impact on the future of U.S. medicine. Written in relatable and accessible language, the book also proposes regulatory reforms for government and medical professionals that will enable technological advancements while maintaining personal and public health standards.
Colonizing Madness
In Colonizing Madness Jacqueline Leckie tells a forgotten story of silence, suffering, and transgressions in the colonial Pacific. It offers new insights into a history of Fiji by entering the Pacific Islands’ most enduring psychiatric institution—St Giles Psychiatric Hospital—established as Fiji’s Public Lunatic Asylum in 1884. Her nuanced study reveals a microcosm of Fiji’s indigenous, migrant, and colonial communities and examines how individuals and communities lived with the label of madness in an ethnically complex island society. Tracking longitudinal change from the 1880s to the present in the construction and treatment of mental disorder in Fiji, the book emphasizes the co...
Fear of Theory
In historiography, many interesting theoretical perspectives on biography have emerged in recent years, from forensics to structure and microhistory. Biographers themselves, though, often fear the study of the genre - needlessly, as these eighteen engaging new essays demonstrate.
Desperate Remedies
A sweeping history of American psychiatry--from the mental hospital to the brain lab--that reveals the devastating treatments doctors have inflicted on their patients (especially women) in the name of science and questions our massive reliance on meds. For more than two hundred years, disturbances of the mind--the sorts of things that were once called "madness"--have been studied and treated by the medical profession. Mental illness, some insist, is a disease like any other, whose origins can be identified and from which one can be cured. But is this true? In this masterful account of America's quest to understand and treat everything from anxiety to psychosis, one of the most provocative th...
