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Ideal for drug discovery scientists and medicinal chemists with an interest in antiviral drug discovery and development, this book provides a complete overview of the latest progress in the field, recent advances and the challenges that remain in developing these highly pathogenic agents.
This volume provides an overview of recent advances in our understanding of the biology of marburg- and ebolaviruses. It focuses on four essential areas: 1) ecology, outbreaks and clinical management, 2) disease, pathogenesis and protection, 3) virus replication inside the cell, and 4) molecular tools for virus study and taxonomy. For 50 years, these viruses have spilled over sporadically and without warning from their wildlife reservoirs, often causing major outbreaks and high fatalities. The consequences can be devastating, with a clear potential for global reach, as demonstrated by the 2013 West African outbreak of Ebola virus, which led to over 28,000 reported cases across three continen...
In this original and innovative work, Yu boldly tackles the increasingly influential collaborative translation phenomenon, with special reference to China. She employs the unique perspective of an ethnographer to explore how citizen translators work together as they select, translate, edit and polish translations. Her area of particular interest is the burgeoning yet notably distinctive world of the Chinese internet, where the digital media ecology is with Chinese characteristics. Through her longitudinal digital ethnographic fieldwork in Yeeyan, Cenci and other online translation platforms where the source materials usually come from outside China, Yu draws out lessons for the various actor...
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