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Nanotechnology can treat diseases by site-specific and target-oriented delivery of precise medicines. Nanomaterials improve the efficacy of drugs and selective diagnosis. The book covers detection and treatment. It explains the use of nanocarriers for a variety of diseases such as cardiovascular and respiratory diseases, cancer, and ulcerative colitis. It includes topical, transdermal, and ocular drug delivery and combined medication delivery.
This new volume covers recent trends of NDDS in the management of the most frequently occurring chronic diseases. The authors outline the different materials that can help prepare NDDS with desired properties. The book looks at NDDS applications for central nervous system (CNS) diseases, including Alzheimer’s and Parkinson’s as well as for HIV, cancer diabetes, asthma and respiratory complications, and diabetic retinopathy. Chapters also look at the use of NDDS in herbal drug delivery, the involvement of artificial intelligence in development of NDDS, and more. This new volume provides an informative overview of the current scope of NDDS for chronic diseases as well as its future development, including how artificial intelligence can be used in novel formulations. The book will prove useful for research scholars and researchers.
This book appraises the role of lipid-based drug delivery systems (LBDDSs) with respect to the bioavailability and controlled delivery of complex drug molecules for improving their clinical viability. It covers the latest developments and advancements in the field of drug delivery, and explores and compiles information on the current situation of lipid-based formulations used as versatile excipients and all their possible routes to improve therapeutic benefits. The book discusses novel formulations such as depot formulations, micro- and nanoemulsions, solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), liposomes, nanoliposomes, micelles, nanosuspensions, lipid implants an...
This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoreti...
Green Sustainable Process for Chemical and Environmental Engineering and Science: Recent Advances in Nanocarriers covers nanocarrier synthesis techniques, as well as methods for encapsulating bioactive compounds. It explores the tests carried out to evaluate their pharmacological properties, in addition to investigating the recent results of clinical tests carried out for some nanocarriers. This book also addresses the most recent advances in nanocarriers and their diverse applications in modern medicine for the treatment of diseases and diagnostics. Nanocarriers play an important role in improving the treatment of diseases and diagnostic imaging as they can deliver medicines to specific loc...
Targeted Drug Delivery Novel approaches in targeted drug delivery for both small molecule and biopharmaceutical drugs Targeted Drug Delivery explores a new frontier in drug research that has become a focus for developing novel medications. The work discusses a wide range of approaches for targeting small molecules as well as peptide and macromolecular drugs, from prodrugs to drug conjugates to drug carriers and devices, helping readers to stay up to date on the latest developments in the field. The following key topics are addressed: Antibody conjugates, prodrugs, and suicide gene therapeutics Protac technology for selectively degrading target proteins Delivery of nucleic acid drugs Novel drug carriers, such as liposomes, vesicles, and nanoparticles Unmet medical needs for which there is a large market potential, such as viral infections and cancer For chemists, pharmacologists, and professionals in the wider pharmaceutical industry, Targeted Drug Delivery is a comprehensive guide on how to solve the greatest challenge in treating many diseases: delivering a pharmaceutically active substance to the target tissue in the body.
This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-d...
This book covers various aspects of cancer chemoprevention, including an overview of chemoprevention in the process of tumorigenesis; the roles of various phytochemicals, functional foods, and dietary interventions in disease prevention; and techniques such as cancer stem cell targeting, nano-formulations, and so forth. The nutrigenomic and epigenetic effects of natural products at the molecular and genetic levels are also covered alongside their potential for additive and synergistic effect, as well as overcoming drug resistance. The key selling features of the book are as follows: Discusses holistic and comprehensive areas of chemoprevention Includes diverse techniques, such as cancer stem...