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Chirality in Liquid Crystals
  • Language: en
  • Pages: 513

Chirality in Liquid Crystals

Describes the main aspects of chirality in liquid crystals, and points out some of the open questions of current research. The chapters review the highlights of the important topics and questions.

Chirality in Industry II
  • Language: en
  • Pages: 432

Chirality in Industry II

This second volume of Chirality in Industry contains new case histories from a wide range of contributors from industry or with strong industrial connections. While it is intended that the new volume will stand on its own, Volumes I and II taken together present an up-to-date and comprehensive picture of the technologies required to produce optically active compounds on a multi-kilogramme to high tonnage scale as well as illustrating the breadth of application of these technologies; the pharmaceuticals, agrochemicals, electronics, food, flavour and fragrance industries are all represented. Chirality in Industry II All new case histories Unique industrial perspective on chiral technology Emph...

The Origin of Chirality in the Molecules of Life
  • Language: en
  • Pages: 164

The Origin of Chirality in the Molecules of Life

Few times an unsolved issue in science has dealt with a larger number of approaches or theories intending to shed light on it and few times this has been done from so different, often orthogonal perspectives. This book covers a hot topic, one of the unsolved problems not just in chemistry, but in science

Chirality
  • Language: en
  • Pages: 376

Chirality

  • Type: Book
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  • Published: 2002
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  • Publisher: Unknown

The physical chemistry of chirality touches on many different chemical fields and as these fields become increasingly sophisticated there is a need for an updated molecular-level text about how the chemistry actually takes place. This volume fills that need by providing current information on a variety of topics, including chiral recognition, spectroscopy, vibrations of chiral molecules, chiral surfaces and theoretical issues in chirality.

Chirality and Biological Activity of Drugs
  • Language: en
  • Pages: 216

Chirality and Biological Activity of Drugs

  • Type: Book
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  • Published: 1995-09-11
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  • Publisher: CRC Press

This book brings together the theoretical, commercial, and practical aspects of chirality and biological activity of drugs and acts as a ready reference for the effects of enantiomers of drug substances.

Chirality in Drug Research
  • Language: en
  • Pages: 370

Chirality in Drug Research

Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals. The two editors from academia and a major pharmaceutical company have assembled an experienced, international team who provide first-hand practical advice and report previously unpublished data. In the first section, the isolation of chiral drugs from natural sources, their production in enzymatic processes and the resolution of racemic mixtures in preparative chromatography are outlined in separate chapters. For the section on qualitative and quantitative analysis, enantioselective chromatographic methods are presented as well as optical methods and CE-MS, while the final section deals with the pharmacology, pharmacokinetics and metabolic aspects of chiral drugs, devoting whole chapters to stereoselective drug binding and modeling chiral drug-receptor interactions. With its unique industry-relevant aspects, this is a must for medicinal and pharmaceutical chemists.

Origin of Chirality in the Molecules of Life
  • Language: en
  • Pages: 242

Origin of Chirality in the Molecules of Life

This book provides an interdisciplinary review of one of the great unsolved mysteries that has fascinated scientists for over 150 years: the origin of chirality in biomolecules. Current advances in fields as diverse as space exploration, prebiotic chemistry and high-energy physics may help to provide an answer. Important pieces of information will come from observations at the two frontiers of science: outer space and the subatomic world. Observation of distant planets, galaxies, and even actual sampling of celestial objects from beyond the solar system are projects currently underway. At the other end of the spectrum, there are experiments that study the elemental properties of matter, such...

Chirality in Supramolecular Assemblies
  • Language: en
  • Pages: 722

Chirality in Supramolecular Assemblies

Supramolecular chemistry deals with the organisation of molecules into defined assemblies using non-covalent interactions, including weaker and reversible interactions such as hydrogen bonds, and metal-ligand interactions. The aspect of stereochemistry within such chemical architectures, and in particular chirality, is of special interest as it impacts on considerations of molecular recognition, the development of functional materials, the vexed question of homochirality, nanoscale effects of interactions at interfaces, biocatalysis and enzymatic catalysis, and applications in organic synthesis. Chirality in Supramolecular Assemblies addresses many of these aspects, presenting a broad overvi...

Chirality in Drug Design and Development
  • Language: en
  • Pages: 406

Chirality in Drug Design and Development

  • Type: Book
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  • Published: 2004-03-15
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  • Publisher: CRC Press

Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characterist

Chirality
  • Language: en
  • Pages: 258

Chirality

The phenomenon of chirality occurs in many disciplines of natural sciences, such as elementary particle physics, chemistry of molecules, biopolymers and crystals, pharmacology, biology (snails, winding plants), and medicine (handedness). Review articles are widely available for most of these fields and written for the respective experts. This book gives for the first time an interdisciplinary comprehensive treatment of chirality. Ten well-known scientists describe the present state of the art in different fields in introductory review articles without going into detail. Most importantly, the book is more than an accumulation of different chapters insofar as biomolecular homochirality is traced back to the chirality of elementary particles in atomic nuclei. The authors have attempted to present chemistry for physicists and physics for chemists, etc. Any scientist who is engaged in chirality may benefit from the present survey.