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Lignans are a class of natural products found mainly in plants. They have a wide variety of structures and exhibit a range of potent biological activities. Lignans are also well-known components of a number of widely eaten foods and are frequently studied for their dietary impact. Owing to these factors, lignans have been extensively studied by scientists from a large number of disciplines. This collection of research and review articles describes topics ranging in scope from the recent isolation and structural elucidation of new lignans, strategies towards the chemical synthesis of lignans, assessment of their biological activities and potential for further therapeutic development. Research showing the impact of lignans in the food and agricultural industries is also presented.
A gorgeously illustrated co-publication with Christine Burgin by “one of the world’s great essayists” (The New York Times). With a guide to the illustrations by Mary Wellesley. Angels have soared through Western culture and consciousness from Biblical to contemporary times. But what do we really know about these celestial beings? Where do they come from, what are they made of, how do they communicate and perceive? The celebrated essayist Eliot Weinberger has mined and deconstructed, resurrected and distilled centuries of theology into an awe-inspiring exploration of the heavenly host. From a litany of angelic voices, Weinberger’s lyrical meditation then turns to the earthly counterparts, the saints, their lives retold in a series of vibrant and playful capsule biographies, followed by a glimpse of the afterlife. Threaded throughout Angels & Saints are the glorious illuminated grid poems by the eighteenth-century Benedictine monk Hrabanus Maurus. These astonishingly complex, proto-“concrete” poems are untangled in a lucid afterword by the medieval scholar and historian Mary Wellesley.
Incidence and mortality of atherosclerosis and coronary heart disease (CHD) vary considerably among races, populations and ethnic groups. Some individuals with low levels of risk factors succumb early to disease while many others with a high risk profile do not. CHD clusters in families and is manyfold increased in first degree relatives of persons with an early onset of the disease. Such studies provide compelling evidence of the high degree of heritability of CHD and its risk factors. This book consolidates the available evidence for the roles of genetics in atherosclerosis, its correlates and its sequelae. It presents and discusses the methodology currently used to elucidate the role of g...
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The novelist and philosopher Iris Murdoch and the painter Harry Weinberger engaged in over twenty years of close friendship and intellectual discourse, centred on sustained discussion of the practice, teaching and morality of art. This book presents a reappraisal of Murdoch’s novels – chiefly, three mature novels, The Sea, The Sea (1978), Nuns and Soldiers (1980) and The Good Apprentice (1985), and two enigmatic late novels, The Green Knight (1993) and Jackson’s Dilemma (1995) – which are perceived through the prism of her discourse with Weinberger. It draws on a run of almost 400 letters from Murdoch to Weinberger, and on Murdoch’s philosophical writings, Weinberger’s private wr...
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