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The Life of a Virus
We normally think of viruses in terms of the devastating diseases they cause, from smallpox to AIDS. But in The Life of a Virus, Angela N. H. Creager introduces us to a plant virus that has taught us much of what we know about all viruses, including the lethal ones, and that also played a crucial role in the development of molecular biology. Focusing on the tobacco mosaic virus (TMV) research conducted in Nobel laureate Wendell Stanley's lab, Creager argues that TMV served as a model system for virology and molecular biology, much as the fruit fly and laboratory mouse have for genetics and cancer research. She examines how the experimental techniques and instruments Stanley and his colleagues developed for studying TMV were generalized not just to other labs working on TMV, but also to research on other diseases such as poliomyelitis and influenza and to studies of genes and cell organelles. The great success of research on TMV also helped justify increased spending on biomedical research in the postwar years (partly through the National Foundation for Infantile Paralysis's March of Dimes)—a funding priority that has continued to this day.
Modeling, Simulation and Optimization of Fluid Dynamic Applications
This book describes recent collaborations combining the expertise of applied mathematicians, engineers and geophysicists within a research training group (RTG) on "Modeling, Simulation and Optimization of Fluid Dynamic Applications”, funded by the Deutsche Forschungsgemeinschaft (DFG). The focus is on mathematical modeling, adaptive discretization, approximation strategies and shape optimization with PDEs. The balanced research program is based on the guiding principle that mathematics drives applications and is inspired by applications. With this leitmotif the RTG advances research in Modeling, Simulation and Optimization by an interdisciplinary approach, i.e., to stimulate fundamental ed...
Myths, Martyrs, and Modernity
This volume in honour of Jan N. Bremmer contains the contributions of numerous students, colleagues, and friends offered to him on the occasion of his 65th birthday. Throughout his career, Bremmer has distinguished himself as an internationally renowned scholar of religion both past and present, including first and foremost Greek and Roman religion, but also early Christianity and post-classical developments in religion and spirituality. In line with these three main areas of Bremmer’s research, the volume is divided into three parts, bringing together contributions from distinguished scholars in many fields. The result is a diverse book which provides a broad spectrum of original ideas and innovative approaches in the history of religions, thus reflecting the nature of the scholarship of Bremmer himself.
Reproduction, Race, and Gender in Philosophy and the Early Life Sciences
Investigates the impact of theories of reproduction and heredity on the emerging concepts of race and gender at the end of the eighteenth and the beginning of the nineteenth centuries. Focusing on the late eighteenth and early nineteenth centuries, this volume highlights the scientific and philosophical inquiry into heredity and reproduction and the consequences of these developing ideas on understandings of race and gender. Neither the life sciences nor philosophy had fixed disciplinary boundaries at this point in history. Kant, Hegel, and Schelling weighed in on these questions alongside scientists such as Caspar Friedrich Wolff, Johann Friedrich Blumenbach, and Karl Ernst von Baer. The essays in this volume chart the development of modern gender polarizations and a naturalized, scientific understanding of gender and race that absorbed and legitimized cultural assumptions about difference and hierarchy.
Disputed Inheritance
A root-and-branch rethinking of how history has shaped the science of genetics. In 1900, almost no one had heard of Gregor Mendel. Ten years later, he was famous as the father of a new science of heredity—genetics. Even today, Mendelian ideas serve as a standard point of entry for learning about genes. The message students receive is plain: the twenty-first century owes an enlightened understanding of how biological inheritance really works to the persistence of an intellectual inheritance that traces back to Mendel’s garden. Disputed Inheritance turns that message on its head. As Gregory Radick shows, Mendelian ideas became foundational not because they match reality—little in nature ...
Molecular World
A compelling and innovative account that reshapes our view of nineteenth-century chemistry, explaining a critical period in chemistry’s quest to understand and manipulate organic nature. According to existing histories, theory drove chemistry’s remarkable nineteenth-century development. In Molecular World, Catherine M. Jackson shows instead how novel experimental approaches combined with what she calls “laboratory reasoning” enabled chemists to bridge wet chemistry and abstract concepts and, in so doing, create the molecular world. Jackson introduces a series of practice-based breakthroughs that include chemistry’s move into lampworked glassware, the field’s turn to synthesis and...
Genetics in the Madhouse
"In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages. Genetics in the Madhouse is the untold story of how the collection and sorting of hereditary data in mental hospitals, schools for 'feebl...
Muller's Lab
Many structures in the human body are named after Johannes Muller, one of the most respected anatomists and physiologists of the 19th century. Muller taught many of the leading scientists of his age, many of whom would go on to make trail-blazing discoveries of their own. Among them were Theodor Schwann, who demonstrated that all animals are made of cells; Hermann Helmholtz, who measured the velocity of nerve impulses; and Rudolf Virchow, who convinced doctors to think of disease at the cellular level. This book tells Muller's story by interweaving it with those of seven of his most famous students.Muller suffered from depression and insomnia at the same time as he was doing his most importa...
Histories of Fetal Knowledge Production in Sweden
In this timely and richly illustrated book, a group of multidisciplinary scholars explores the uses and handlings of fetuses, still-born, reproductive organs, and pregnant bodies for knowledge production, including the development of vaccines and pharmaceuticals, in Sweden over five hundred years. By examining the conflicted values and balancing acts of a variety of actors, such as medical experts, legal officials, policymakers, media professionals, disability organizations, and women’s movements, it demonstrates how the uses of aborted fetuses for research generated public controversy and became regulated by ethics and law in Sweden. Contributors are: Eva Åhrén, Annika Berg, Elisabet Björklund, Maria Björkman, Maja Bondestam, Isa Dussauge, Helena Franzén, Solveig Jülich, Francis Lee, Tove Paulsson Holmberg, Morag Ramsey, Anton Runesson, Helena Tinnerholm Ljungberg, and Anna Tunlid.
About Method
Scientists’ views on what makes an experiment successful have developed dramatically throughout history. Different criteria for proper experimentation were privileged at different times, entirely new criteria for securing experimental results emerged, and the meaning of commitment to experimentation altered. In About Method, Schickore captures this complex trajectory of change from 1660 to the twentieth century through the history of snake venom research. As experiments with poisonous snakes and venom were both challenging and controversial, the experimenters produced very detailed accounts of their investigations, which go back three hundred years—making venom research uniquely suited f...
