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Biological Basis of Sex Differences in Psychopharmacology
Sex matters! Are there differences between the sexes when it comes to brain function and the behaviours that result? This volume attempts to answer this fundamental question. If the answer is ‘yes’ then this should impact upon our approach to treating mental illness in humans, and to modelling it in animals, as we look for aetiological and pharmacological solutions.
Frontiers in Psychiatry
This book reviews key recent advances and new frontiers within psychiatric research and clinical practice. These advances either represent or are enabling paradigm shifts in the discipline and are influencing how we observe, derive and test hypotheses, and intervene. Progress in information technology is allowing the collection of scattered, fragmented data and the discovery of hidden meanings from stored data, and the impacts on psychiatry are fully explored. Detailed attention is also paid to the applications of artificial intelligence, machine learning, and data science technology in psychiatry and to their role in the development of new hypotheses, which in turn promise to lead to new di...
The Impact of Stress on Cognition and Motivation
Stress has a broad impact on animals’ behavior, profoundly affects brain regions involved on cognition and motivation and, when maladaptive, is also a trigger for neuropsychiatric disorders. This book focuses on advances in understanding how stressful events impact cognition and motivation, and the neural mechanisms that mediate their effects. Additionally, this book seeks to highlight the most recent efforts to identify individual factors that can alter an organism’s response to stressful stimuli, and to describe pharmacological and non-pharmacological interventions that can mitigate the deleterious effects of stress on cognition and motivation.
Sex Differences in Brain Function and Dysfunction
Does sex matter when it comes to brain function? This volume attempts to answer this very important question which is of relevance to the disciplines of psychology, neuroscience, psychiatry and neurology. Understanding how brain function and resultant behaviors may differ between the sexes impacts upon our knowledge of the pathology and development of treatments for various neurological and psychiatric disorders, particularly those that show significant sex differences in either prevalence and/or manifestation of symptoms. This volume covers three main themes of research into sex differences in basic neurobiology, psychology, preclinical research and clinical research. It begins by exploring...
Perinatal Psychopharmacology
This book focuses on recent advances in research and practical recommendations regarding the use of psychotropic drugs during pregnancy and lactation, two important social and psychological life events for women. In addition to the social context, including the addition of a new family member, many women experience the occurrence or recurrence of psychiatric disorders during the perinatal period. Psychiatric disorders during this period can have negative effects on the fetus, infant and other children in the family, and can result in functional impairment among mothers. The book offers a comprehensive overview of psychopharmacological treatments for nearly all specific psychiatric conditions (e.g. bipolar disorder, panic disorder, obsessive-compulsive disorder) and includes chapters on clinical approaches to treating these disorders. As such, it will appeal to a wide readership, including psychiatrists, obstetricians, gynecologists and pediatricians.
Mommy Brain
Do you sometimes have the feeling that your brain is going to mush and that your baby is literally sucking the life out of your neurons? Don' t worry, you' re not losing your mind! In fact, your brain is getting a complete makeover and focusing on new areas of learning which are essential for parenting. In this book, Dr Jodi Pawluski questions our relationship with motherhood and explores, in an unprecedented way, the fantastic universe of the maternal, and parental, brain. Drawing on numerous scientific studies, including her own neuroscience research and experience, she provides insight into how your brain really changes with motherhood, and why.
Avoidance: From Basic Science to Psychopathology
Coping has a myriad of facets: knowledge concerning the circumstances of threats to emotional and physical well being, the ability to meet immediate needs to mitigate, the potential for recurrence, the ability to apply efforts and resources to manage recurrence, and the complex assessment of competing motivations and changing circumstances. Successful coping is measured in the efficiency of efforts in balance with the degree of threat and likelihood of future occurrence. As one means of coping, avoidance encompass thoughts and efforts toward prevention of future aversive experiences and events. Anxiety disorders exemplify an extreme bias toward avoidance. A diathesis learning model focuses research efforts on individual vulnerabilities to acquire and express avoidance, the neurobiology of avoidance learning and its attendant circuitry. A fundamental understanding of avoidance through a diathesis learning model offers will facilitate the development of effective treatment protocols in alleviating anxiety disorders.
Issues in Medical Research Ethics
With the advances of medicine, questions of medical ethics have become more urgent and are now considered of great social and political significance. An innovatively designed, activity-based workbook, this text was prepared using papers and case studies collected from several countries in the European Union. It reflects the issues and concerns that confront clinical practitioners throughout Europe and elsewhere today and presents varying national responses in law and policy to these concerns, as identified by ethicists, lawyers, theologians and practitioners. The problems they examine include the relationship between medical research and medical practice, elementary regulations of medical research, the complexity of informed consent, and the role of the sponsor or scientific community.
