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Relying on practical examples from the authors’ experience, this book provides a thorough and modern approach to controlling and monitoring microbial contaminations during the manufacturing of non-sterile pharmaceuticals. Offers a comprehensive guidance for non-sterile pharmaceuticals microbiological QA/QC Presents the latest developments in both regulatory expectations and technical advancements Provides guidance on statistical tools for risk assessment and trending of microbiological data Describes strategy and practical examples from the authors’ experience in globalized pharmaceutical companies and expert networks Offers a comprehensive guidance for non-sterile pharmaceuticals microbiological QA/QC Presents the latest developments in both regulatory expectations and technical advancements Provides guidance on statistical tools for risk assessment and trending of microbiological data Describes strategy and practical examples from the authors’ experience in globalized pharmaceutical companies and expert networks
The Manual of Commercial Methods in Clinical Microbiology 2nd Edition, International Edition reviews in detail the current state of the art in each of the disciplines of clinical microbiology, and reviews the sensitivities, specificities and predictive values, and subsequently the effectiveness, of commercially available methods – both manual and automated. This text allows the user to easily summarize the available methods in any particular field, or for a specific pathogen – for example, what to use for an Influenza test, a Legionella test, or what instrument to use for identification or for an antibiotic susceptibility test. The Manual of Commercial Methods in Clinical Microbiology, 2...
You strike a woman, you strike a rock. On the 44th anniversary of the women's defiance campaign, this book pays tribute to the many women who have shaped the hsitory of South Africa.
One of the most popular mirrors for princes, Christine de Pizan's Epistre Othea (Letter of Othea) circulated widely in England. Speaking through Othea, the goddess of wisdom and prudence, in the guise of instructing Hector of Troy, Christine advises rulers, defends women against misogyny, and articulates complex philosophical and theological ideals. This volume brings together for the first time the two late medieval English translations, Stephen Scrope's precise translation The Epistle of Othea and the anonymous Litel Bibell of Knyghthod, once criticized as a flawed translation. With substantial introductions and comprehensive explanatory notes that attend to literary and manuscript traditions, this volume contributes to the reassessment of how each English translator grappled with adapting a French woman's text to English social, political, and literary contexts. These new editions encourage a fresh look at how Christine's ideas fit into and influenced the English literary tradition.
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Christine de Pizan's Livre de la Cité des Dames (1405) is justly renowned for its full-scale assault on the misogynist stereotypes which dominated the culture of the Middle Ages. Rosalind Brown-Grant locates the Cité in the context of Christine's defence of women as it developed over a number of years and through a range of different texts. Arguing that Christine tailored her critique of misogyny according to the genre in which she was writing and the audience she was addressing, this study shows that Christine's case for women nonetheless had an underlying unity in its insistence on the moral, if not the social, equality of the sexes. Whilst Christine may not have been a radical in modern feminist terms, she was able to draw upon the cultural resources of her day in order to construct an intellectual authority for herself that challenged the prevailing orthodoxy of the day.
This book provides a state-of-the-art account by academic respiratory physicians and senior pharmaceutical industry personnel on the development of new drugs for asthma, allergy and COPD. It contains 80 chapters of highly condensed information, presented in an attractive, reader-friendly format with much use of tables, figures and diagrams. In addition to summarizing the diverse range of current approaches, this handbook also looks into the future, considering many topics that are promising, but have only emerged in the last few years. Developments within established drug categories such as beta-2-agonists, steroids and leukotriene antagonists are also reviewed. Never before has a single book brought together so many pharmaceutical drug developers sharing their experience on such a wide range of respiratory topics!
The term arthrogryposis describes a range of congenital contractures that lead to childhood deformities. It encompasses a number of syndromes and sporadic deformities that are rare individually but collectively are not uncommon. Yet, the existing medical literature on arthrogryposis is sparse and often confusing. The aim of this book is to provide individuals affected with arthrogryposis, their families, and health care professionals with a helpful guide to better understand the condition and its therapy. With this goal in mind, the editors have taken great care to ensure that the presentation of complex clinical information is at once scientifically accurate, patient oriented, and accessible to readers without a medical background. The book is authored primarily by members of the medical staff of the Arthrogryposis Clinic at Children's Hospital and Medical Center in Seattle, Washington, one of the leading teams in the management of the condition, and will be an invaluable resource for both health care professionals and families of affected individuals.
"The catalogue ... is truly excellent and makes an important contribution to the study of Greek Art." --Bryn Mawr Classical Review "An overwhelming volume. The subject matter ... is described in great detail in nine chapters. Essential." --Choice This catalogue documents a major exhibition at the Getty Villa that was the first ever to focus on ancient Athenian terracotta vases made by techniques other than the well-known black- and red-figure styles. The exhibition comprised vases executed in bilingual, coral-red gloss, outline, Kerch-style, white ground, and Six's technique, as well as examples with added clay and gilding, and plastic vases and additions. The Colors of Clay opens with an introductory essay that integrates the diverse themes of the exhibition and sets them within the context of vase making in general; a second essay discusses conservation issues related to several of the techniques. A detailed discussion of the techniques featured in the exhibition precedes each section of the catalogue. More than a hundred vases from museums in the United States and Europe are described in depth.