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X-ray Contrast Agent Technology
This book documents the fascinating history of radiological techniques that use contrast agents. The text includes many of the fundamental documentary sources that bring to life the social and scientific background of the discoveries, the personalities of the discoverers, and implementation of new technologies. Such agents when used with X-rays allow clinicians to distinguish anatomical structures with nearly identical densities. Focus is on urological and angiographic uses of contrast agents. Key selling features: Documents and thoroughly references the history of contrast agent development Reviews the priority and importance of patents Discusses the role that important individual scientists and leading research institutions have played in technology development and implementation
The Practices of Human Genetics
That concern about human genetics is at the top of many lists of issues requiring intense discussion from scientific, political, social, and ethical points of view is today no surprise. It was in the spirit of attempting to establish the basis for intelligent discussion of the issues involved that a group of us gathered at a meeting of the International Society for the History, Philosophy, and Social Studies of Biology in the Summer of 1995 at Brandeis University and began an exploration of these questions in earlier versions of the papers presented here. Our aim was to cross disciplines and jump national boundaries, to be catholic in the methods and approaches taken, and to bring before rea...
Metallopharmaceuticals II
Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, receives a comprehensive summary and critical overview of a topic of hight current interest written by leading international experts.
Contemporary Metabolism
It is abundantly clear that a number of subtle abnormalities in hypothalamic function are associated with human obesity. Some hormonal abnormalities-the diminished growth hormone responses, for example-are critically dependent on increased caloric intake and are quickly reversible with weight loss. Others, such as the blunted prolactin response to acute hypoglycemia, may persist in the reduced-obese state. Still others (e. g. , the blunted ACTH responses to insulin induced hypoglycemia) may, in some patients, first appear in the reduced-obese state. It remains uncertain whether any of these abnormalities is ever antecedent to the presence of obesity. Obviously, it is difficult to plan experi...
Norway's Pharmaceutical Revolution
The pharmaceutical revolution that gathered pace in the 1930s delivered a plethora of almost magical new drugs such as penicillin, streptomycin, cortisone, and the birth control pill. This revolution grew from academic-business relationships in five countries: USA, Germany, Great Britain, Switzerland, and France. Many other countries tried and failed to replicate this success, yet a handful of Scandinavia companies made important breakthroughs in a narrow band of specialities. This is the story of how one Norwegian company— Nyegaard & Co. —achieved international success from the 1970s onwards with a breakthrough product facilitating X-ray pictures of the soft tissues of the body. The com...
Molecular Aspects of Membrane Phenomena
This book is a compilation of formal presentations made during a three-day invitational conference at Battelle Research Center in Seattle, Washington. The purpose of organizing and publishing the proceedings of the conference is to provide a comprehensive survey of present knowledge on the determinants of membrane structure, the molec ular specificity of membrane function, and the dynamic properties of membranes. Each presentation was followed by discussions which, be cause of their informal and spontaneous character, have not been in cluded in this publication. Molecular studies of biological membrane phenomena have progressed over the past decade to the point where it is now realistic to e...
Handbook of Organizational Learning and Knowledge
This is an overview of how the concept of organisational learning emerged, how it has been used and debated, and where it may be going.
Evolutionary Theory
The natural world is infinitely complex and hierarchically structured, with smaller units forming the components of larger systems: genes are components genomes, cells are building blocks of tissues and organs, individuals are members of populations, which, in turn, are parts of species. In the face of such awe inspiring complexity, scientists need tools like the hierarchy theory of evolution, which provides a theoretical framework and an interdisciplinary research program that aims to understand the way complex biological systems work and evolve. The multidisciplinary approach looks at the structure of the myriad intricate interactions across levels of organization that range from molecules to the biosphere. Evolutionary Theory: A Hierarchical Perspective provides an introduction to the theory, which is currently driving a great deal of research in bioinformatics and evolutionary theory. Written by a diverse and renowned group of contributors, and edited by the founder of Hierachy Theory Niles Eldredge, this work will help make transparent the fundamental patterns driving living sytems.
