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Epigenetics
  • Language: en
  • Pages: 469

Epigenetics

Illuminating the processes and patterns that link genotype to phenotype, epigenetics seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utility of this approach for understanding complex biological systems in development, disease, and evolution. Chapters cover such topics as morphogenesis and organ formation, conceptual foundations, and cell differentiation, and together demonstrate that the integration of epigenetics into mainstream developmental biology is essential for answering fundamental questions about how phenotypic traits are produced.

Recent Trends in Nonlinear Partial Differential Equations II
  • Language: en
  • Pages: 354

Recent Trends in Nonlinear Partial Differential Equations II

This book is the second of two volumes which contain the proceedings of the Workshop on Nonlinear Partial Differential Equations, held from May 28-June 1, 2012, at the University of Perugia in honour of Patrizia Pucci's 60th birthday. The workshop brought together leading experts and researchers in nonlinear partial differential equations to promote research and to stimulate interactions among the participants.

The Geometry of Heisenberg Groups
  • Language: en
  • Pages: 321

The Geometry of Heisenberg Groups

"The three-dimensional Heisenberg group, being a quite simple non-commutative Lie group, appears prominently in various applications of mathematics. The goal of this book is to present basic geometric and algebraic properties of the Heisenberg group and its relation to other important mathematical structures (the skew field of quaternions, symplectic structures, and representations) and to describe some of its applications. In particular, the authors address such subjects as signal analysis and processing, geometric optics, and quantization. In each case, the authors present necessary details of the applied topic being considered." "This book manages to encompass a large variety of topics being easily accessible in its fundamentals. It can be useful to students and researchers working in mathematics and in applied mathematics."--BOOK JACKET.

Mammalian Artificial Chromosomes
  • Language: en
  • Pages: 277

Mammalian Artificial Chromosomes

In 1996, we organized a workshop, inter alia, at the National Research Co- cil in Milan under the generous sponsorship of the European Science Foun- tion. On that occasion, a small group of investigators convened from many countries and presented early evidence of the possibility of assembling basic units of mammalian chromosomes into artificial constructs (or, indeed, red- ing the relevant components to more manageable dimensions and defined c- stitution). Progress in the following years has been slow but steady. Many scientists who took part in the workshop have since been engaged in active and prod- tive research. It goes to the credit of Humana Press to have realized the need for a book ...

Gene function in schistosomes: recent advances towards a cure
  • Language: en
  • Pages: 156

Gene function in schistosomes: recent advances towards a cure

Schistosomes are human parasites distributed worldwide in tropical and sub-tropical latitudes, especially in developing countries and impoverished regions. These neglected tropical disease (NTD) pathogens causes debilitating illnesses, which include hepatosplenomegaly, hepatic fibrosis, haemorrhagic necrotic ulcerations in the intestinal mucosa, urogenital tract diseases, in addition to cardiopulmonary, renal and neurologic lesions due to egg accumulation in the liver, intestines, uro-genital tissues and other sites. Urogenital schistosomiasis is a risk factor for bladder cancer and increases the risk of transmission of HIV infection. Despite extensive effort to control this NTD over the yea...

Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations
  • Language: en
  • Pages: 340

Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations

  • Type: Book
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  • Published: 2015-11-04
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  • Publisher: Springer

This volume provides in-depth reviews of model systems that exemplify the arms race in host-pathogen interactions. Somatic adaptations are responsible for the individualization of biological responses to the environment, and the continual struggle between host immune systems and invading pathogens has given rise to corresponding processes that produce molecular variation. Whether in mollusks or human beings, various host somatic mechanisms have evolved independently, providing responses to counter rapidly-changing pathogens. The pathways they utilize can include non-heritable changes involving RNA and post-translational modifications, or changes that produce somatic DNA recombination and mutation. For infectious organisms such as protozoans and flatworms, antigenic variation is central to their survival strategy. Evolving the ability to evade the host immune system not only increases their chances of survival but is also necessary for successful re-infection within the host population.

Analysing Gene Expression
  • Language: en
  • Pages: 992

Analysing Gene Expression

This book combines the experience of 225 experts on 900 pages. Scientists worldwide are currently overwhelmed by the ever-increasing number and diversity of genome projects. This handbook is your guide through the jungle of new methods and techniques available to analyse gene expression - the first to provide such a broad view of the measurement of mRNA and protein expression in vitro, in situ and even in vivo. Despite this broad approach, detail is sufficient for you to grasp the principles behind each method. In each case, the authors weigh up the advantages and disadvantages, paying particular attention to the automated, high-throughput processing demanded by the biotech industry. Complet...

Theory Of The Navier-stokes Equations
  • Language: en
  • Pages: 246

Theory Of The Navier-stokes Equations

This volume collects the articles presented at the Third International Conference on “The Navier-Stokes Equations: Theory and Numerical Methods”, held in Oberwolfach, Germany. The articles are important contributions to a wide variety of topics in the Navier-Stokes theory: general boundary conditions, flow exterior to an obstacle, conical boundary points, the controllability of solutions, compressible flow, non-Newtonian flow, magneto-hydrodynamics, thermal convection, the interaction of fluids with elastic solids, the regularity of solutions, and Rothe's method of approximation.

Reaction Diffusion Systems
  • Language: en
  • Pages: 432

Reaction Diffusion Systems

  • Type: Book
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  • Published: 2020-10-07
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  • Publisher: CRC Press

"Based on the proceedings of the International Conference on Reaction Diffusion Systems held recently at the University of Trieste, Italy. Presents new research papers and state-of-the-art surveys on the theory of elliptic, parabolic, and hyperbolic problems, and their related applications. Furnishes incisive contribution by over 40 mathematicians representing renowned institutions in North and South America, Europe, and the Middle East."

Schistosomiasis: Host-Parasite interactions
  • Language: en
  • Pages: 603

Schistosomiasis: Host-Parasite interactions

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