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Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new techniques. The protocols reflect the latest "hands on" knowledge of key laboratories in this still fast-moving field. Newcomers will benefit from the proven step-by-step protocols, which include helpful practical advice; experienced antibody engineers will appreciate the new ideas and approaches. The book is an invaluable resource for all those engaged in antibody research and development.
The first book to offer a cutting-edge discussion of contemporary travel writing in German, Anxious Journeys looks both at classical tropes of travel writing and its connection to current debates. The rich contemporary literature of travel has been the focus of numerous recent publications in English that seek to understand how travel narratives, with their distinctive representations of identities, places, and cultures, respond to today's globalized, high-speed world characterized by the dual mass movements of tourism and migration. Yet a corresponding cutting-edge discussion of twenty-first-century travel writing in German has until now been missing. The fourteen essays in Anxious Journeys...
The theory of imperialism is usually associated with some of the ‘big names’ in the history of European Marxism, such as Lenin, Rosa Luxemburg, Rudolf Hilferding and Nikolai Bukharin, alongside whom the English Progressive John Hobson is usually mentioned. However, little is known about the development of Marxist theory on this subject besides the books of these figures. This volume assembles for the first time the main documents of the international debate on imperialism that took place in the Second International during the period 1898–1916. It assesses the contributions of the individual participants to the developing theory of imperialism, placing them in the context of contemporary political debates.
In this book, first published in 1992, the author examines the polemic fought by German Social-Democratic Party leaders and intellectuals Karl Kautsky and Eduard Bernstein against what they perceived to be misunderstandings of Marxism propagated by members of the Social-Democratic Federation (SDF) in England and by the socialist leader Wilhelm Liebknecht in Germany. The debate raised basic questions of socialist theory, including whether the program of Marx and Engels called for scholarly study, parliamentary democracy, and gradual social evolution, or for Utopian speculation, economic collapse, and violent rebellion.
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This is the first book-length functional-typologically inspired crosslinguistic study of comitatives and related categories such as the instrumental. On the basis of data drawn from 400 languages world-wide (covering all major phyla and areas), the authors test and revise a variety of general linguistic hypotheses about the grammar and cognitive foundations of comitatives. Three types of languages are identified according to the morphological treatment of the comitative and its syncretistic association with other concepts. It is shown that the structural behaviour of comitatives is areally biassed and that the languages of Europe tend to diverge from the majority of the world's languages. Th...
This text explores the state of affairs in 2003 regarding the implementation of the principle in the law of the sea in different areas: like, pollution of the marine environment, conservation and management of living marine resources and transboundary transports of radioactive and hazardous wastes.
Claimants of paranormal abilities have always attracted controversy and fascination, and sometimes rigorous study by scientists. Charles Bailey, an Australian medium, was seemingly able to materialize different objects--animate and inanimate--under conditions which made it difficult to conceive how they could have been normally produced. Sumitra Singh, a woman of Northern India who in 1984 became subject to epileptic-type seizures, claimed to be possessed by spirits of the dead. Franck Kluski was a Polish poet, banker and physical medium who specialized in both human and animal materializations. This biographical dictionary contains profiles of 330 psychics worldwide from Tony Agpaoa to Elen...
What is the relationship between colonialism and culture? Jeff Bowersox answers this question by looking at how young Germans imagined the wider world around them during the age of high imperialism.