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Toll-Like Receptor Activation in Immunity vs. Tolerance
The innate immune system has evolved means to recognize and react suitably to foreign entities such as infectious agents. In many cases infectious microorganisms threaten the integrity and function of the target organs or tissues; therefore, consequent to their recognition the immune system becomes activated to ensure their elimination. Toll-like receptors (TLR) constitute a family of receptors specialized in the recognition of molecular patterns typically associated with infectious agents. Different TLRs exist, each selective for molecular entities and motifs belonging to a specific pathogen group. Consequently, it is thought that the molecular nature of invading microorganisms activates sp...
Managing Diabetes
A critical study of diabetes in the popular imagination Over twenty-nine million people in the United States, more than nine percent of the population, have some form of diabetes. In Managing Diabetes, Jeffrey A. Bennett focuses on how the disease is imagined in public culture. Bennett argues that popular anecdotes, media representation, and communal myths are as meaningful as medical and scientific understandings of the disease. In focusing on the public character of the disease, Bennett looks at health campaigns and promotions as well as the debate over public figures like Sonia Sotomayor and her management of type 1 diabetes. Bennett examines the confusing and contradictory public depicti...
Blockchain and the Law
“Blockchains will matter crucially; this book, beautifully and clearly written for a wide audience, powerfully demonstrates how.” —Lawrence Lessig “Attempts to do for blockchain what the likes of Lawrence Lessig and Tim Wu did for the Internet and cyberspace—explain how a new technology will upend the current legal and social order... Blockchain and the Law is not just a theoretical guide. It’s also a moral one.” —Fortune Bitcoin has been hailed as an Internet marvel and decried as the preferred transaction vehicle for criminals. It has left nearly everyone without a computer science degree confused: how do you “mine” money from ones and zeros? The answer lies in a techno...
Multiple Sclerosis
Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS pat...
Neuroimaging, Part I
Neuroimaging, Part One, a text from The Handbook of Clinical Neurology illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This first volume specifically covers a description of imaging techniques used in the adult brain, aiming to bring a comprehensive view of the field of neuroimaging to a varying audience. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading...
Diabetes and Viruses
This book will assemble the views of many of the world's experts in the field of viruses and diabetes. It will look critically at some unanswered questions, in the field. Among these, How do viruses destroy or modify the pancreatic islet? Which viruses are involved? What is the role of virus-induced cytokines> Could vaccines prevent virus-induced diabetes? Until recent technological advances, progress in the understanding of the relationship between viruses and diabetes has been hampered. New technologies are helping shed new light on these mysteries. This will be the first comprehensive volume on this topic.
What You Need to Know about Diabetes
This accessibly written book provides a broad introduction to diabetes—its signs, symptoms, and effects on the body; how it can be managed and prevented; and the issues and controversies that surround this all-too-common condition. Today, nearly one in 10 Americans has diabetes, and complications from diabetes are now the seventh leading cause of death in the United States. Rates of type 2 diabetes are on the rise, despite the fact that it's considered a highly preventable condition. What You Need to Know about Diabetes is a part of Greenwood's Inside Diseases and Disorders series. This series profiles a variety of physical and psychological conditions, distilling and consolidating vast co...
BART
An insider’s “indispensible” behind-the-scenes history of the transit system of San Francisco and surrounding counties (Houston Chronicle). In the first-ever history book about BART, longtime agency spokesman Michael C. Healy gives an insider’s account of the rapid transit system’s inception, hard-won approval, construction, and operations, warts and all. With a master storyteller’s wit and sharp attention to detail, Healy recreates the politically fraught venture to bring a new kind of public transit to the West Coast. What emerges is a sense of the individuals who made (and make) BART happen. From tales of staying up until 3:00 a.m. with BART pioneers Bill Stokes and Jack Evers...
Bringing the Mediterranean Into Your Garden
Mediterranean garrigue landscapes are extraordinarily beautiful: alternating mounds of silver and green, textured leaves, flashes of colour and intoxicating scents combine to delight the senses and rival any cultivated garden with half the work. This book offers inspiration and expert advice on growing the plants and adopting a new more natural way of gardening. Mediterranean plants are diverse and adapted to a wide range of environments and weather conditions. They are of course ideally suited to regions which experience long periods of seasonal drought but many will also withstand periods of high rainfall and extreme cold making this book essential reading for temperate-zone gardeners seeking the Mediterranean look. Some understanding of plant ecology is essential for success and Filippi shares his expert knowledge acquired from decades of research. How a plant interacts with its environment, other plants, and other living things indicates what it needs to flourish in a garden setting.
