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Molecular Mechanisms Of Drug Action
In this book the targets of drug action are the central focus - whether they be enzymes in a pathway or membrane-bound receptors and ion channels. This approach distinguishes the book from others in the f ield which consider the subject mainly in terms of disease.; The introductory chapter is concerned with the basic principles that cover enzyme inhibition and receptor binding by drugs. The next seven chapters deal with drugs that modulate biochemical pathways, both of synthesis and breakdown, while the last four chapters are concerned with organizational structures of the cell.; The book brings together the state of knowledge with respect to drug action and emphasizes mechanistic aspects of drug action. It encompasses the modes of action of drugs for infectious disease and those for endogenous conditions. There is a listing of reviews and essay questions are provided for each chapter.
Practical Guide to Evidence
Practical Guide to Evidence provides a clear and readable account of the law of evidence, acknowledging the importance of arguments about facts and principles as well as rules. This fifth edition has been revised and updated to address recent changes in the law and debates on controversial topics such as surveillance and human rights. Coverage of expert evidence has also been expanded to include forensic evidence, bringing the text right up-to-date. Including enhanced pedagogical support such as chapter summaries, further reading advice and self-test exercises, this leading textbook can be used on both undergraduate and professional courses.
Poor Relations
The sixty years between 1773 and 1833 determined British paramountcy in India. Those years were formative too for British Eurasians. By the 1820s Eurasians were an identifiable and vocal community of significant numbers particularly in the main Presidency towns. They were valuable to the administration of government although barred in the main from higher office. The ambition of their educated elite was to be accepted as British subjects, not to be treated as native Indians, an ambition which was finally rejected in the 1830s.
Empire of Neglect
Following the publication of Adam Smith’s The Wealth of Nations, nineteenth-century liberal economic thinkers insisted that a globally hegemonic Britain would profit only by abandoning the formal empire. British West Indians across the divides of race and class understood that, far from signaling an invitation to nationalist independence, this liberal economic discourse inaugurated a policy of imperial “neglect”—a way of ignoring the ties that obligated Britain to sustain the worlds of the empire’s distant fellow subjects. In Empire of Neglect Christopher Taylor examines this neglect’s cultural and literary ramifications, tracing how nineteenth-century British West Indians reoriented their affective, cultural, and political worlds toward the Americas as a response to the liberalization of the British Empire. Analyzing a wide array of sources, from plantation correspondence, political economy treatises, and novels to newspapers, socialist programs, and memoirs, Taylor shows how the Americas came to serve as a real and figurative site at which abandoned West Indians sought to imagine and invent postliberal forms of political subjecthood.
The Sense of Hearing
The Sense of Hearing is a truly accessible introduction to auditory perception that is intended for students approaching the subject for the first time, and as a foundation for more advanced study. The second edition has been thoroughly revised throughout, and included new chapters on music, hearing impairment, and a new appendix describing research methodologies. In clear and authoritative prose, the fundamental aspects of hearing are addressed. The reader is introduced to the nature of sound and the spectrum, and the anatomy and physiology of the auditory system. Basic auditory processes including frequency selectivity, loudness and pitch perception, temporal resolution, and sound localiza...
Incidence Algebras
This work covers the maximal and prime ideals of the incidence algebra, derivations and isomorphisms, radicals and additional ring-theoretic properties. Combinatorial discussions include a study of the Mobius function, reduced incidence subalgebras, and the coalgebra approach to incidence algebras.;College or university bookstores may order five or more copies for a special student price, which is available on request from Marcel Dekker.
Temperature and Toxicology
Thermoregulation is vital for survival but the interplay between toxic insults and thermoregulatory mechanisms is often poorly understood. Temperature and Toxicology: An Integrative, Comparative, and Environmental Approach is the first major text to study the integrative thermoregulatory responses of mammals that are exposed to toxicants. Because e
Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2004
The 7th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2004, was held in Saint-Malo, Brittany, France at the “Palais du Grand Large” conference center, September 26–29, 2004. The p- posaltohostMICCAI2004wasstronglyencouragedandsupportedbyIRISA, Rennes. IRISA is a publicly funded national research laboratory with a sta? of 370,including150full-timeresearchscientistsorteachingresearchscientistsand 115 postgraduate students. INRIA, the CNRS, and the University of Rennes 1 are all partners in this mixed research unit, and all three organizations were helpful in supporting MICCAI. MICCAI has become a premier international conference with in-depth - pe...
Philosophy of Education: The Key Concepts
This new edition of Philosophy of Education: The Key Concepts is an easy to use A-Z guide summarizing all the key terms, ideas and issues central to the study of educational theory today. Fully updated, the book is cross-referenced throughout and contains pointers to further reading, as well as new entries on such topics as: Citizenship and Civic Education Liberalism Capability Well-being Patriotism Globalisation Open-mindedness Creationism and Intelligent Design. Comprehensive and authoritative this highly accessible guide provides all that a student, teacher or policy-maker needs to know about the latest thinking on education in the 21st century.'
The Names of the Fallen
Este Libro en un enfoque diferente critica a las instituciones y gobiernos que hicieron posible que este conflicto empezara. Ademas es un sincero homenaje al valor y el sacrificio de los honorables soldados norteamericanos y mienbros de la coalicion que perdieron sus vidas; al pueblo de Iraq que sufrio las horrendas consequencias de la guerra en forma directa.
