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Along the last several decades, it has been progressively appreciated that immunology plays an overwhelming role in the physiology and pathophysiology of most organs, tissues, and biological systems in multicellular organisms. Accordingly, several immunological parameters are used in research and clinical laboratories with the purpose of investigating, diagnosing, and monitoring a variety of pathological conditions. The rapidly evolving field of laboratory testing in immunology poses several challenges to professionals working in research and clinical laboratories, medical practice, educational activities, in vitro diagnostic industry, and regulatory agencies. Regular analytes, such as album...
China’s most sophisticated system of computational astronomy was created for a Mongol emperor who could neither read nor write Chinese, to celebrate victory over China after forty years of devastating war. This book explains how and why, and reconstructs the observatory and the science that made it possible. For two thousand years, a fundamental ritual of government was the emperor’s “granting the seasons” to his people at the New Year by issuing an almanac containing an accurate lunisolar calendar. The high point of this tradition was the “Season-granting system” (Shou-shih li, 1280). Its treatise records detailed instructions for computing eclipses of the sun and moon and motio...
In this issue of Immunology & Allergy Clinics, guest editor Dr. Elizabeth J. Phillips brings her considerable expertise to the topic of Drug Hypersensitivity. Top experts in the field cover key topics such as perioperative anaphylaxis; telemedicine in drug hypersensitivity; aspirin-exacerbated respiratory disease; pediatric drug allergy; and more. - Contains 15 relevant, practice-oriented topics including excipient allergy; recognizing drug hypersensitivity in skin of color; allergy to radiocontrast dye; MRGRPX2 and its role in non-IgE-mediated mast cell activation; and more. - Provides in-depth clinical reviews on drug hypersensitivity, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
In the first decade of the twentieth century while other intellectuals were concerned with translating works of political and scientific import into Chinese, Wang Kuo-wei (1877-1927) looked to Western philosophy to find answers to the fundamental questions of human life. He was the first Chinese to translate Schopenhauer and Nietzsche into Chinese and to apply their views of aesthetics to Chinese literature. The influence of their concepts of genius and the sublime can easily be seen in his J en-chien tz'u-hua 人間詞話. Wang was also indebted to Chinese critics for the development of his theories regarding the sphere of individuality that each poem represents (ching-chieh), a theory that places him among the ranks of China's greatest literary critics. Innovative as he was in his concepts of poetry, however, Wang chose to convey those concepts in the traditional form of poetic criticism, the tz'u-hua, or "talks on poetry." Thus this translation of the complete edition of his Jen-chien tz'u-hua not only adds to the Westerner's knowledge of Chinese literary criticism but also provides insight into the way in which Chinese communicated with each other about their literature.
This resource guides prescribers, pharmacists, and regulators with an update on the recent expansion of basic and clinical knowledge that forms a framework for understanding cutaneous reactions. This understanding will lead, in turn, to better outcomes and decisions in treatment and management, both in the clinic and in the life cycle of drug development. The skin is a common target for adverse drug events and even mild rashes can be part of life-threatening syndromes. Patients and practitioners often face important decisions about therapy after a drug eruption, including treatment, cross-reactivity with future pharmaceuticals, genetic considerations and dealing with long-term sequelae after a reaction. An international team of experts and leaders in the field share their story and insights into the scientific details and relevant clinical context.